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There is a current concept of minimal invasive treatment strategies. A thermoresponsive injectable bone substitute can be moulded into the irregular shape of a bone cavity and can get hardened after application, thus limiting the requirements of complicated surgeries. The injectable bone substitute provides an alternative treatment for those patients who require hard tissue regeneration when other surgical interventions/strategies may not be effective or may cause more disadvantages than advantages [1-2]. Injectable are flowable polymeric systems and have ability to hold bone fillers, and other small molecules (antibiotics, amino acids etc.). In vivo, these injectables get cured at body temperature and adopt any desired shape with tuned mechanical properties and degradation rate. Injectable composites are excellent material for controlled release of drugs, biomolecules and bone fillers.
20941803126
