Bioengineering vascularized microtissues

Jun 30, 2022, 11:00 AM
20m
Room: S3 A

Room: S3 A

Speaker

Barrias, Cristina (i3S/INEB-Instituto de Investigação e Inovação em Saúde/Instituto de Engenharia Biomédica)

Description

Modular tissue-engineering approaches provide a promising strategy for building complex living structures from the bottom-up, through the co-assembly of microscale tissue units. Using biofabrication tools, multiple modular units of parenchymal, stromal, and vascular tissues can be rationally combined to recreate structurally/functionally different compartments of human organs. Microtissue units present a high surface area, which facilitates the diffusion/mobility of oxygen, molecules, and cells through interstitial gaps, affording a useful tool to generate densely cellularized 3D constructs. In this talk, we outline different approaches to engineering vascularized microtissues and describe some of their applications in the fields of regenerative medicine and in vitro modeling.

31451703204

Presentation materials

There are no materials yet.