Can biofabrication technologies help to facilitate biobanking of tissue engineered products?

Jun 28, 2022, 1:30 PM
Room: S4 B

Room: S4 B


Moroni, Lorenzo (Maastricht University - MERLN Institute for Technology-Inspired Regenerative Medicine, Complex Tissue Regeneration department)


"Organs are complex systems, comprised of different tissues, proteins, and cells, which communicate to orchestrate a myriad of functions in our bodies. Technologies are needed to replicate these structures towards the development of new therapies for tissue and organ repair, as well as for in vitro 3D models to better understand the morphogenetic biological processes that drive organogenesis. To construct tissues and organs, biofabrication strategies are being developed to impart spatiotemporal control over cell-cell and cell-extracellular matrix communication, often through control over cell and material deposition and placement. These technologies could also play a role in protecting seeded or encapsulated cells in case of off-the-shelf products are desired for biobanking purposes.
Here, we present some of our most recent advancements in biofabrication that enabled the control of cell activity, moving towards enhanced tissue regeneration as well as the possibility to create more complex 3D in vitro models to study biological processes, with a particular attention to biobanking requirements to preserve tissue construct functionality before and after storage."


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