Speaker
Description
In this seminar, I will provide a basic overview of the developmental mechanisms underlying the emergence of functional areas in the cerebral cortex. I will start by providing an overview of studies performed in rodents. Subsequently, I will transition to describe our studies in human, highlighting similarities and differences in progenitor cell diversity between mice and humans, I will subsequently describe how single cell transcriptomics and single cell epigenomics have helped us to identify modules of co-regulated and co-functional genes during human cortical development. Finally, I will describe our latest work on deciphering the role of developmental signaling pathways in promoting cortical arealization in the human brain.
31451707929
