Conveners
S05 Additive manufacturing in tissue repair: current status and obstacles toward a daily clinical practice
- Veronika Hruschka (Ludwig Boltzmann Institute for Traumatology )
- Mohammad Alkhraisat (BTI Biotechnology Institute)
"Regenerative implants are most ideally suited for individualized production using additive manufacturing. For regulatory market access, if not containing cells or tissue compounds making them ATMP’s, the choice is between serially produced scaffolds, patient-adapted designs or custom-made devices that require a prescription. While it seems helpful that custom-made products do not get a CE...
Medical additive manufacturing (aka medical 3d-printing) has received increasing attention in the past years with research applications in many clinical domains, particularly in surgical disciplines (e.g. orthopedic, oral, cardiovascular). In some domains medical 3d-printing has established itself in daily clinical practice, however the question remains if is it ready for broad clinical use....
Introduction
Additive manufacturing approaches have the potential to address a number of major challenges in the field of meniscus tissue engineering (TE), in particular the development of anatomically defined grafts with a spatial architecture and composition mimetic of the native tissue. Here, we report a novel method to engineer organized soft tissues, with a collagen architecture and...
Introduction:
Melt Electrowriting (MEW) is a novel 3D printing method that allows fabricating scaffolds with different designs, including structural gradients. The gradient scaffolds can be useful, for example, in the engineering of tissue interfaces, which are characterized by gradually changing mechanical and biological properties [1]. Nonetheless, the prediction of such scaffolds’...
Introduction
Spinal cord injury (SCI) induces paralysis by severing the long axons of neurons and recovery is inhibited by poor regrowth rates. As neural cells are electroactive, electrical stimulation (ES) may present a promising method of promoting axonal regrowth when applied in conjunction with electroconductive (EC) biomaterials1. To efficiently deliver ES to regrowing motor and sensory...
Combining different materials or material-properties in 3D printing is garnering widespread attention due to the wide range of possibilities that it provides to produce parts which are more functional and have improved properties. This paper presents the combination of lithography-based ceramic manufacturing, a vat photopolymerization technology capable of realizing high resolution 3D printing...
Additive manufacturing allows for a wide range of freeform and complex shapes to be made with little or no manufacturing limitations. The most significant benefit of additive manufacturing in medical applications is that it allows for the creation of patient-specific medical products such as implants. Individualized implants are considered to provide greater comfort, precise fit, user...
Current medical devices certification is challenging due to the update in the regulatory norms and the appearance of gaps (grey zone) due to advances in both the materials and the fabrication technology. A key aspect when reaching a higher level of technology readiness is to have a comprehensive view of the entire process that will lead to the conformity of the devise with the medical device...
