Conveners
S08 Antimicrobial biomaterials for bone regeneration
- Joanna Sadowska (Royal College of Surgeons in Ireland)
- Fergal O'Brien (Tissue Engineering Research Group, Department of Anatomy and Regenerative Medicine, RCSI University of Medicine and Health Sciences; Trinity Center for Biomedical Engineering, Trinity College Dublin; Advanced Materials and Biomedical)
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Boccaccini, Aldo (University of Erlangen-Nuremberg)6/28/22, 11:00โฏAMinvited lect.-online
"Bioactive glasses (BGs) are being increasingly investigated as antibacterial materials for developing scaffolds for bone tissue engineering (TE). Such applications are based on the biochemical reactions occurring on the BG surface in contact with the biological environment, which involve the (controlled) release of biologically active ions during BG scaffold degradation. Such ions are capable...
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Mele, Andrea (University of Sheffield )6/28/22, 11:20โฏAMpodium presentation
Introduction
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Bone tumour removal, traumas with large defects or infections, and degenerative diseases are the main catastrophic events impeding complete bone healing. Autologous and allogenic bone grafting, and biologically inert metallic devices have limitations such as non-availability of autogenous bone, risk of infectious disease transmission, subsequent surgical removal, and bacterial... -
Gamna, Francesca (Politecnico di Torino )6/28/22, 11:30โฏAMpodium presentation
Introduction:
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Implant infection, due to bacterial contamination, is a significant problem that represents one of the main causes of implant loss over time. In addition, the incidence of antibiotic resistance is steadily increasing, and alternative ways to fight or prevent infection have become the subject of biomedical research, and several surface modification and coating techniques have... -
Arango-Ospina, Marcela (Institute of Biomaterials, University of Erlangen-Nuremberg)6/28/22, 11:40โฏAMpodium presentation
Introduction
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Since the discovery of bioactive glasses (BG) in the late 60s [1], the research in this area has significantly increased to obtain compositions with multiple functionalities not only from the materials aspect but also to provide a favorable biological response for tissue regeneration. BGs have the ability to react with the surrounding environment and bond to hard tissue. This... -
Martinez Perez, David (Warsaw University of Technology )6/28/22, 11:50โฏAMpodium presentation
Introduction: In the last years, partly given to the changes in the age structure of the population, there has been a skyrocketing increase of the number of orthopaedic surgeries [1]. With the rising number of implantations, the absolute number of complications is inevitably increasing at the same pace, causing not only distress for the patients but also a significant economic burden [2]. One...
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Gribova, Varvara (University of Strasbourg, Inserm UMR 1121)6/28/22, 12:00โฏPMpodium presentation
"Introduction
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Implantation of biomedical devices is followed by immune response to the implant, as well as occasionally bacterial and yeast/fungi infections (1-3). In this context, new implant materials and coatings that deal with medical device-associated complications are required. Antibacterial and anti-inflammatory materials are also required for wound healing applications, especially in... -
Mosina, Marika (Rudolfs Cimdins Riga Biomaterials Innovations and Development Centre of RTU, Institute of General Chemical Engineering, Faculty of Materials Science and Applied Chemistry, Baltic Biomaterials Centre of Excellence, Headquarters at Riga Technical Universit )6/28/22, 12:10โฏPMpodium presentation
INTRODUCTION: Bacterial antibiotic resistance increases every year, creating an urgent need to develop new antibacterial materials. Gallium has been studied since the 1970s as an effective treatment for bone diseases and has recently shown antibacterial activity against different bacterial strains. Therefore, gallium doped hydroxyapatite (GaHAp) could be used as an antibacterial agent. The aim...
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Genoud, Katelyn (Tissue Engineering Research Group, Department of Anatomy and Regenerative Medicine, RCSI University of Medicine and Health Sciences; Trinity Center for Biomedical Engineering, Trinity College Dublin; Advanced Materials and Biomedical Engineering Research)6/28/22, 12:20โฏPMpodium presentation
Introduction
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Bone infections (osteomyelitis) are difficult to treat due to the formation of biofilms, antibiotic resistance, and limited penetration of systemic antibiotics to infection site(1). Highly-porous collagen-hydroxyapatite (C-HA) scaffolds have proven capacity to regenerate critical-sized bone defects in vivo and human clinical trials(2). However, they still lack appropriate...