Conveners
S21+S44 Biophysical Therapies - External energy to push internal regeneration + Nano Magnetic platforms - an attractive opportunity for advancing TERM products to the clinic
- Peter Dungel
- Luminita Labusca (National Institute of Research and Development for Technical Physics (NIRDTP) Iasi, Romania, Emergency County Hospital Saint Spiridon Iasi, Romania )
- Alicia El Haj
- Paul Slezak
Recent efforts are beginning to explore the application of extracorporeal shock wave therapy (ESWT) to near lung tissue and transcranial indications. This is driven by a desire to expand the well establish therapeutic and regenerative benefits to a new group of patients. Through mechanotransduction of the incoming pressure pulse, a cascade of biochemical responses is triggered within the...
Impaired wound healing and infections present a major concern for our health systems. Combined with the steady increase of antibiotic resistances and lack of new antibiotic drugs,
there is a pressing need for alternative treatment options, such as antimicrobial light-based therapies. While the germicidal properties of UV light have already been used for a long time, its negative side effects,...
"INTRODUCTION: Iron oxide based magnetic nanomaterial, magnetic nanoparticles (MNPs) and magnetic nanowires (NW) are versatile tools in biology and medicine. MNPs-mediated drug delivery is tested for regenerative medicine (RM) purposes as well as for tumour treatment and diagnostics. Stem cell mediated delivery represents a modality to target remote, metastatic tumors or regenerative sites for...
"INTRODUCTION: When assessing the interaction between nanomaterials and cells, an important step is to image the effects induced by the material to the cell membrane. In order to evaluate the results of the interaction process, scanning electron microscopy (SEM) is typically used. Commonly, an important step during the preparation of biological cell samples for SEM is represented by the...
"Introduction
Mechanotransduction is a key process in many developmental, physiological and pathological processes in bone. Mechanosensitive ion channels such as Piezo1 and TREK1 are the bonafide mechanotransducers that are critical for various biological processes, plays a critical role in bone regeneration1, 2. We already reported that the Magnetic ion channel activation (MICA) technology...
"Introduction: Inflammation is a physiological process in healing however, persistent inflammation signals hold deleterious consequences to the tissue and contributes to the inhibition of regeneration. Resolving inflammation remains an unmet challenge with great impact in the management of chronic inflammatory disorders and for the treatment of tissue injuries. Interleukin 4 (IL4) is a...
"Introduction: The currently available treatments for inflammation often target the symptoms but not the causes, leading to an ineffective management of persistent inflammatory conditions.
Due to the central role of macrophages (Mφ) in the inflammatory response, and overall in healing, innovative strategies to fine-tune the states and functionalities of Mφ may unveil the pathophysiology of...
