Conveners
S26 Combined Korea-EU Symposium: "Bone from fat: Two distinct 17-18 year journeys in bone regeneration with adipose stromal/stem cells"
- Gunil Im (Dongguk University BMC)
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Im, Gunil (Dongguk University BMC)6/30/22, 1:30โฏPMinvited lecture
In this talk, author's decades-long research on inducing bone from adipose stem cell (ASCs) will be introduced, including 1) the exploration of osteogenic potentioal of ASCs versus bone marrow stem cell (BMSCs), 2) investigation of small molecules, peptides, gene transfer to enhance osteogesis, 3) synergistic effect of coculture of ASCs and BMSvs in osteogenesis and angiogenesis, 4) mining of...
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Scherberich, Arnaud (Department of Biomedicine, University of Basel)6/30/22, 1:50โฏPMinvited lecture
This lecture will show how biomaterials and components of the extracellular matrix, i.e. structural proteins and growth factors, affect the osteogenic potential of human adipose-derived mesenchymal stromal cells (ASC). Examples of bone formation by various human adipose derived cells-based engineered matrix/tissue, via either intramembranous or endochondral ossification will be presented. The...
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Stojceski, Filip (Dalle Molle Institute for Artificial Intelligence (IDSIA-SUPSI-USI) )6/30/22, 2:10โฏPMpodium presentation
Objectives
The glucocorticoid receptor (GR) is a nuclear receptor that controls critical biological processes by regulating the transcription of specific genes. GR transcriptional activity is modulated by a series of ligand and coenzymes, where a ligand can act as an agonist or antagonist. GR agonists, such as the glucocorticoids dexamethasone (DEX) and prednisolone, are widely prescribed...
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Bispo, Daniela S. C. (Department of Chemistry, CICECO - Aveiro Institute of Materials (CICECO/UA), University of Aveiro)6/30/22, 2:20โฏPMpodium presentation
The use of mesenchymal stem cells (MSCs) for bone regeneration is a promising alternative to conventional bone grafts. Because local metabolic alterations seem to be critical for bone regeneration, metabolomics (through cell extracts and culture media) may unveil novel information on MSCs osteogenic differentiation,1,2 allowing their behaviour to be understood and potentially guided towards...
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Jesus, Catarina S. H. (Department of Chemistry, CICECO - Aveiro Institute of Materials (CICECO/UA), University of Aveiro)6/30/22, 2:30โฏPMpodium presentation
Mesenchymal stem cells (MSCs) are in the frontline of tissue engineering and regenerative medicine because they have indefinite self-renewal potential, and also exhibit great multilineage differentiation into a variety of tissues such as such as bone, cartilage, and adipose1. In the field of bone tissue engineering, the osteogenesis of MSCs is a promising therapeutic target, and controlling...
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Hutmacher, Dietmar W. (Max Planck Queensland Centre on the Materials Science for Extracellular Matrices, Queensland University of Technology )6/30/22, 2:40โฏPMpodium presentation
Introduction: Lack of sufficient vascularization to support cell viability, growth and function in scaffold guided tissue regeneration (SGTR) is a prevalent challenge facing tissue engineering today. Matching axial vascularization is a regenerative therapeutic approach which incorporates the benefits of flap-based techniques for neo-vascularization to further aid tissue regeneration....
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