Conveners
S40 Injectable scaffolds in tissue engineering
- Beata Niemczyk-Soczynska (Institute of Fundamental Technological Research, Polish Academy of Sciences)
- Irene Lara-Saez
The COVID-19 pandemic has shown how revolutionary treatments based on gene therapeutics has helped overcome a once-in-a-century pandemic and has given new momentum to gene therapy research for a myriad of applications. The field of regenerative medicine is well placed to be a beneficiary whereby, for example, gene therapy might be a valuable tool to avoid the limitations of local delivery of...
"The development of hydrogels for regenerative medicine has progressed to the point where they are now considered one of the best options for successfully regenerating injured tissues. Their structural similarities to the extracellular matrix (ECM) and their versatility make them excellent candidates to mimic a native environment. Indeed, they are easily chemically modified and can be tuned to...
"Introduction: A major challenge in cartilage tissue engineering (TE) is to develop scaffolds capable of providing an instructive biomimetic environment to effectively drive mesenchymal stromal cells (MSCs) differentiation [1]. Hydrogels have emerged as promising biomaterials for this purpose, due to their biocompatibility and ability to mimic the tissue extracellular matrix [2].
Recently,...
"Introduction:
The high number of vascular diseases demand for vascular grafts in various clinical application. Nonetheless, a big hurdle for the use of autologous tissue-engineered vascular grafts (TEVG) is represented by the usually long manufacturing time.Therefore, we here present a biohybrid vascular graft and a bioreactor that can provide distinct conditions such as flow, pressure, and...
"Introduction
The use of non-covalent self-assembly to construct materials has become a prominent strategy in biomaterial science offering practical routes for the construction of increasingly functional materials for a variety of applications ranging from cell culture and tissue engineering to in-vivo cell and drug delivery.[1] A variety of molecular building blocks can be used for this...
"INTRODUCTION
Islet transplantation is a recognised treatment for type 1 diabetes: islets are transplanted into the liver and the procedure can stabilise blood glucose levels. A major limitation for successful clinical islet transplantation is the significant loss of islets post-transplantation due to an immune mediated inflammatory reaction. Etanercept, a TNF blocker that binds specifically...
"Statement of Purpose: The development of a hydrogel that could be injected and cured in vivo has gained increasing attention. Collagen has been widely investigated as a thermogel in which there are a lot of ionic interaction, hydrophobic interaction, and hydrogen bonding; however, it must be chemically crosslinked also. Diels-Alder cycloaddition occur under mild conditions without the need...
