Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Conference 2022

Session

S62 Tissue regeneration by integration of bioinspired materials

S62

Jun 29, 2022, 11:00 AM

ICE Krakow

Conveners

S62 Tissue regeneration by integration of bioinspired materials

• Sandra Van Vlierberghe
• Heungsoo Shin

1001. TBA

Rodríguez-Cabello, José Carlos (University of Valladolid)

6/29/22, 11:00 AM

invited lecture

TBA

582. The Controlled Delivery of Proteoglycan-4 in a Scaffold-Based System for Cartilage Repair Applications

Matheson, Austyn (Royal College of Surgeons in Ireland )

6/29/22, 11:20 AM

podium presentation

"Introduction
Proteoglycan-4 (PRG4) is a mucinous glycoprotein with critical roles in the bio-lubrication of articular cartilage and joint health1. Intra-articular injection of PRG4 protects against cartilage deterioration in in vivo models of osteoarthritis, an effect that is largely attributed to restored bio-lubrication. Thus far, tissue-engineered, collagen-glycosaminoglycan (coll-GAG)...

576. Hybrid 3D-printed hydrogel scaffolds for liver tissue engineering

Carpentier, Nathan (Polymer Chemistry and Biomaterials group, Ghent University )

6/29/22, 11:30 AM

podium presentation

"Introduction
Annually, millions of people die because of liver failure, while the waiting duration for a donor liver is around 12 months.[1] Herein, we target hybrid 3D-printed scaffolds to serve liver tissue engineering(LTE) applications.
As starting materials gelatin in combination with a polysaccharide was used to develop printable hydrogels. As polysaccharides dextran (Dex) and...

572. Combining proteolytic sequences, VEGF-mimetic peptide and laminin-derived peptide within Elastin-Like Recombinamer scaffolds for the spatiotemporal direction of angiogenesis and neurogenesis

González-Pérez, Fernando ( Universidad de Valladolid )

6/29/22, 11:40 AM

podium presentation

"Introduction
The fabrication of three-dimensional (3D) scaffolds able to promote a spatiotemporal guidance of cell infiltration, vascularization and innervation are of great interest in tissue engineering and regenerative medicine (TERM) applications. To this end, peptide sequences displaying fast and slow proteolytic rates towards urokinase plasminogen activator uPA, namely GTAR and DRIR,...

584. TIME COURSE OF ECTOPIC BONE FORMATION IN RATS INDUCED BY rhBMP6 WITHIN AUTOLOGOUS BLOOD COAGULUM WITH CALCIUM PHOSPHATE CERAMIC PARTICLES

Stokovic, Nikola (Laboratory for Mineralized Tissues, School of Medicine University of Zagreb )

6/29/22, 11:50 AM

podium presentation

"Introduction: Osteoinductive bone morphogenetic proteins (BMPs) possess the ability to induce bone formation and therefore have been the basis of osteoinductive devices designed for bone regeneration. Osteogrow C is a novel autologous bone graft substitute comprised of recombinant human Bone Morphogenetic Protein 6 (rhBMP6) within autologous blood coagulum (ABC) with synthetic calcium...

586. Prognostic evaluation of the use of three-dimensional (3D) scaffolds on chronic skin lesions using new biomedical imaging technologies.

Cavallini, Chiara (CNR Institute of Clinical Physiology)

6/29/22, 12:00 PM

podium presentation

"Introduction: Human umbilical cord blood stored in blood banks cannot always be used for hematopoietic stem cell transplantation as up to 80% of stem cells are lower than the cut-off required for such application, being potentially available for non-transfusion applications such as the source of platelet growth factor [1]. In this study, we fabricated a fibrin-based drug delivery system to...

84. HEPARAN SULPHATE ANALOGUE HYDROGELS AS A PLATFORM FOR KIDNEY ORGANOID MATURATION

Fagiolino, Sveva (Department of Complex Tissue Regeneration, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University, the Netherlands)

6/29/22, 12:10 PM

podium presentation

Kidney organoid derived from pluripotent stem cells (PSCs) have gradually become a platform to understand kidney morphogenesis, development and diseased states. Despite the abundant differentiation protocols to obtain relevant renal cell types and organoids, most of these only reach a developmental immature stage (1). We hypothesize that the limited maturation is due to absence of relevant ECM...

574. DIRECTING STEM CELL COMMITMENT IN 3D BIOINSPIRED HYDROGELS BY GROWTH FACTOR SEQUESTRATION USING MOLECULARLY IMPRINTED NANOPARTICLES

Teixeira, Simão P. B. (3B's Research Group, I3Bs—Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine; ICVS/3B's–PT )

6/29/22, 12:20 PM

podium presentation

"Introduction: Growth factors (GFs) are a key component of tissue engineering, but their exogenous administration has proven costly and ineffective. Extracellular matrix-inspired biomaterial approaches have sought to sequester these molecules, regulating their activity and presentation to cell receptors.1 Our previous work has shown that molecularly imprinted nanoparticles (MINPs) can play...