Characterisation of Collagen/Chondroitin Sulfate and Collagen/Hyaluronic Acid Scaffolds to Model the Prostate Cancer Microenvironment.
Nezar Kamal1,, Aamir Hameed1, Ciara Murphy1,2,3, Caroline Curtin1,2,3
1Tissue Engineering Research Group (TERG), Department of Anatomy & Regenerative Medicine, Royal College of Surgeons in Ireland (RCSI), Dublin, Ireland. 2Trinity Centre for...
INTRODUCTION
Idiopathic pulmonary fibrosis (IPF) is a lung disease characterized by excessive remodelling of the extracellular matrix (ECM), where fibroblasts are one of the main producers of ECM components. Our aim is to understand how lung fibroblasts respond to mechanical cues in a healthy or diseased ECM composition. We have created an ex vivo model to mechanically stimulate fibroblasts...
One of the biggest challenges in the field of tumour engineering is providing cells with a proper environment mimicking physiological conditions of cancer from the biomechanical point of view. Hard tissue cancers, such as osteosarcoma, are no exception, especially taking into account the complexity of the bone microenvironment. The golden standard is the use of human-derived tissue-engineered...
Introduction: The Tissue Engineering Resource Center (TERC) was established to serve the established, junior and aspiring investigators and trainees by providing advanced technologies, training and service; as well as students and the general public by providing dissemination and outreach programs. Our ambition is to offer resources that will be transformative to the overall impact of tissue...
