An Osteochondral defect (OCD) refers to an area of local damage in the articular cartilage and in the underlying subchondral bone (SB). Trauma related to an injury, or a long-term chronic disease are the main causes of this defect. Tissue engineering osteochondral scaffolds (OCSs) is a method used for the treatment of OCD. This method could achieve the regeneration of the damaged tissue using...
Introduction:
Petridish-based 2-dimensional (2D) cell culture models are currently used as the first step to test the efficacy of anticancer drugs, but they don’t accurately mimic tumor biology and microenvironment. Moving to 3D models, one of the major concerns is how to assess the drug efficacy. Cell viability is an essential parameter to be monitored to measure cell growth and to assess...
INTRODUCTION
Bioprinting is gaining an ever-increasing research interest thanks to its promising new applications in the field of tissue engineering. The main issue regarding this biofabrication technique is the engineering of suitable bioinks, accommodating both the requirements for fabrication and for cell culture and signalling. Versatile platform bioinks, with easily tailorable...
