3D-Printable biomaterials have potential for fabrication of customized scaffolds for tissue engineering. In the study, methacrylated gelatin (GelMA) and aldehyde-functionalized polyurethane (PU) were synthesized and used to prepare 3D-printable GelMA-PU biomaterials. The GelMA-PU hydrogel and cryogel were optimized for compositions and manufacture processes. The GelMA-PU hydrogel was...
According to estimations of the Global Cancer Observatory, over 2.2 million women were diagnosed with breast cancer in 2020, worldwide. [1] While most often requiring surgical removal of the affected breast tissue, breast reconstruction following mastectomy remains a challenge. [2] Conventional reconstruction techniques, using synthetic prostheses or autologous tissue, are accompanied with...
Introduction
Bone tissue is a vascularized, highly specialized, and hierarchically organized tissue. Nowadays, Tissue Engineering is challenging to recapitulate the structural complexity of physiological bone extracellular matrix (ECM), and biomaterials have been widely investigated [1]. Herein, methacrylated gelatin (GelMA) was largely involved since physico-chemical and mechanical...