Introduction
Mammalian bone growth in length occurred through the process of enochondral bone formation through sequential chains of chondrocytes proliferation and differentiation at the growth plate (GP) 1. The endochondral ossification (EO) process is highly regulated to ensure normal post natal bone development at the epiphyseal growth plate (EGP) 2. The cascade of events during ED is...
INTRODUCTION: Light-assisted additive bio-manufacturing has emerged as a powerful tool for custom fabrication of structurally complex 3D tissue models from stem cells.[1-2] Existing in vitro bone models, however, often lack terminally differentiated bone cells named osteocytes which are crucial for bone homeostasis and functional adaptation in response to mechanical loads. Here, we report...
