Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Conference 2022

Session

PS47 New insights underlying mesenchymal stem cell-mediated bone regeneration

PS47

Not scheduled

ICE Krakow

531. A NOVEL BIOMIMETIC KNEE JOINT BIOREACTOR FOR THE IN VITRO REGENERATION OF OSTEOCHONDRAL LESIONS

Campillo, Noelia (REGEMAT 3D S.L.)

poster

The biomedical sector is experiencing a technological transformation in its attempt to solve current and next future global health issues. The scarcity of organ donors in a growing elderly population accentuates the need to generate new strategies based on the use of cutting-edge technologies for regenerative medicine.
In recent years, the emergence of 3D bioprinting has allowed great...

1015. Amino acid supplementation enhances hBMSCs osteogenic capacities

van Griensven, Martijn (Department of Cell Biology-Inspired Tissue Engineering, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University )

poster

Introduction
Around 10% of long bone fractures display inadequate bone regeneration, leading to delayed- or non-unions. Amino acids have shown to play important roles in bone regeneration. In particular, citrulline has revealed itself as an enhancer of bone regeneration in murine bone defect healing models. Oral citrulline supplementation stimulated callus formation and lead to a balanced...

526. Differences in periodontal ligament stem cells from maxilla and mandible

Malyaran, Hanna (Institute of Pathology, RWTH Aachen University)

poster

Introduction:
Diseases of the periodontium start in general with the recession of the periodontal ligament (PDL) and leads to loosening of the tooth within the alveolar bone. The cementum and periodontal ligament play important roles in physiological tooth function. Therefore, cementum and periodontal ligament regeneration are critical for periodontal regenerative therapy. Decades of clinical...

491. FUNCTIONAL CHARACTERIZATION OF HUMAN BONE MARROW STROMAL CELLS IN VIVO WITH INCREASED THROUGHPUT

Korczak, Adam Aleksander (Laboratory for Cell and Tissue Engineering, Department of Obstetrics, University and University Hospital Zurich)

poster

Introduction:
The human bone marrow (BM) is home to Hematopoietic Stem Cells (HSCs) and Bone Marrow Stromal Cells (hBMSCs) which are known to contain skeletal stem cell populations. Whereas the HSC compartment is well characterized, the identity and function of the hBMSC populations remain obscure and requires thorough investigation. A better understanding of the BM and the accommodated cells...

530. LIQUIFIED MICROCAPSULES: A VERSTILE PLATFORM TO APPLY HIGH HYDROSTATIC PRESSURE TO HUMAN ADIPOSE-DERIVED MESENCHYMAL STEM CELLS FOR OSTEOGENIC DIFFERENTIATION

Ghasemzadeh-Hasankolaei, Maryam (CICECO–Aveiro Institute of Materials, Department of Chemistry, University of Aveiro)

poster

Bone is constantly exposed to a range of macro-scale loading which creates a complex mechanical microenvironment for its resident cells. One such mechanical stress generated is hydrostatic pressure (HP) which plays an important role in cell function and fate determination. Although HP is a constant mechanical cue for bone resident cells, little is known about the effect of this external...