Human induced pluripotent stem cell (hiPSC)-derived kidney organoids have prospective applications ranging from basic disease modelling to personalised medicine. However, there remains a necessity to refine the biophysical and biochemical parameters that govern kidney organoid formation. Differentiation within fully controllable and physiologically relevant 3D growth environments will be...
The generation of human induced pluripotent stem cell (hiPSC)-derived kidney organoids have facilitated novel insights into renal developmental processes and have the potential to provide personalised treatment strategies for patients with end-stage renal disease. Traditional protocols for the directed differentiation of hiPSC-derived kidney organoids have predominantly focused on biochemical...
