"Liver disease is a major healthcare challenge, accounting for around 2 million deaths yearly worldwide. Although liver transplantation is the best way to re-establish normal liver function, less than 10% of transplantation needs are currently met. The EU Horizon 2020 OrganTrans consortium aims to address this issue by developing a liver tissue printing platform for transplantation. In this...
"Introduction: Over the last decade, an increasing relevance has been given to the use of semi-quantitative and quantitative methods to evaluate histological and immunohistochemical images through image analysis software. Most of this software only require image input. However, the usability of classic image processing, including classic segmentation algorithms, is limited. Machine learning...
"Introduction: Bottom-up developmental engineering is showing promising results in skeletal tissue engineering1. In this approach, microtissues are formed from periosteal cells, the main contributors in the formation of the cartilaginous fracture callus. These microtissues can be chondrogenically differentiated towards hypertrophy resulting in a cartilaginous template in vitro which can be...
