Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Conference 2022

Session

PS64 Understanding and preventing early inflammatory events that lead to development of osteoarthritis

PS64

Not scheduled

ICE Krakow

742. Cell based therapies for OA treatment: the secret of successful cartilage regeneration is hidden in the stem cells’ origin.

Bina, Valentina (Department of Molecular medicine, University of Pavia)

poster

"INTRODUCTION: Osteoarthritis (OA) is the most common arthropathy and a leading cause of pain and disabilities worldwide. Globally, OA affected more than 300 million people; however, despite its prevalence and importance, even economically, the comprehension of its molecular background is limited. Moreover, as OA is characterized by a complex molecular network, it is unlikely that targeting a...

743. Cell morphology as a biological fingerprint for describing chondrocyte phenotype under acute and chronic IL-1β mediated inflammation in healthy and osteoarthritic chondrocytes

Selig, Mischa (1G.E.R.N. Research Center for Tissue Replacement, Regeneration & Neogenesis, Dept. of Orthopedics and Trauma Surgery)

poster

"Introduction: High IL-1β levels are often found in osteoarthritic (OA) joints. Moreover, IL-1β credibly induces post-traumatic OA. Since cell morphology is an important regulator of cell behavior, we investigated how acute vs. chronic IL-1β dynamically changes multifaceted aspects of cell morphology in healthy and OA chondrocytes in relation to phenotypic outcome.
Methods: Acute inflammation...

741. EFFECTS OF LACTIC ACID ON SYNOVIAL FLUID

Kakati, Nayanjyoti (Department of Chemical engineering, Indian Institute of Technology Guwahati)

poster

"Introduction: Synovial fluid is a viscous liquid found inside the joints of bones. This fluid helps in minimizing the bone to bone contact and facilitates movements of joints via lubrication. The key component of synovial fluid which gives its viscous property is hyaluronic acid (HA). Apart from HA it also consists of various proteins like albumins, gamma globulins etc. Synovial fluid has a...