"INTRODUCTION: Osteoarthritis (OA) is the most common arthropathy and a leading cause of pain and disabilities worldwide. Globally, OA affected more than 300 million people; however, despite its prevalence and importance, even economically, the comprehension of its molecular background is limited. Moreover, as OA is characterized by a complex molecular network, it is unlikely that targeting a...
"Introduction: High IL-1β levels are often found in osteoarthritic (OA) joints. Moreover, IL-1β credibly induces post-traumatic OA. Since cell morphology is an important regulator of cell behavior, we investigated how acute vs. chronic IL-1β dynamically changes multifaceted aspects of cell morphology in healthy and OA chondrocytes in relation to phenotypic outcome.
Methods: Acute inflammation...
"Introduction: Synovial fluid is a viscous liquid found inside the joints of bones. This fluid helps in minimizing the bone to bone contact and facilitates movements of joints via lubrication. The key component of synovial fluid which gives its viscous property is hyaluronic acid (HA). Apart from HA it also consists of various proteins like albumins, gamma globulins etc. Synovial fluid has a...
