Conveners
S16-2 Biomaterials from nature based on extracellular matrices: engineering, repopulation and regenerative potential
- Andrea Barbero
- Sylvia Nรผrnberger
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Douglas, Timothy (Lancaster University )6/28/22, 3:30โฏPMinvited lecture
Whey protein isolate (WPI) is an inexpensive byproduct from the dairy industry which can be processed into autoclavable hydrogels with high compressive strength which support the adhesion, growth and differentiation of cells which can be applied in bone regeneration. Furthermore, WPI hydrogels can solubulized hydrophobic molecules and hence serve as a delivery vehicule for hydrophobic...
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Alamรกn-Dรญez, Pilar (Multiscale in Mechanical and Biological Engineering, Instituto de Investigaciรณn en Ingenierรญa de Aragรณn (I3A), University of Zaragoza)6/28/22, 3:50โฏPMpodium presentation
INTRODUCTION
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Creating biofunctional scaffolds could potentially meet the demand for patients suffering from bone defects without having to rely on donors or autologous transplantation. 3D printing has emerged as a promising tool to fabricate scaffolds with high precision and accuracy by computer design using patient-specific anatomical data1. Among other relevant key points for 3D-printed... -
Al Enezy-Ulbrich, Miriam Aischa (Institute for Technical and Macromolecular Chemistry, Research Area Functional and Interactive Polymers, RWTH Aachen University, and DWI - Leibniz Institute for Interactive Materials )6/28/22, 4:00โฏPMpodium presentation
"Introduction
In present times, implant development focusses on optimizing biocompatibility, mechanical strength, and reproducibility. Although cardiovascular implants currently available on the market are medically established and therefore widely used, they have a limited lifetime which also impacts the mechanical properties and functionality. Additional issues are the formation of blood...
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Casado Losada, Isabel (Department of Orthopedics and Trauma-Surgery, Division of Trauma-Surgery, Medical University of Vienna. Ludwig Boltzmann Institute for Traumatology, the Research Center in Cooperation with AUVA. Austrian Cluster for Tissue Regeneration. )6/28/22, 4:10โฏPMpodium presentation
"Introduction
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Cell infiltration is essential for the repopulation of dense materials in tissue engineering. During that process, several factors, such as scaffold topography, mechanical properties or porosity play a key role. These acquire special importance when designing the materials to substitute and regenerate articular cartilage. Because of their similar structure and composition,... -
Aliaa, Nik (Division of Biomaterials and Tissue Engineering, UCL Eastman Dental Institute, University College London )6/28/22, 4:20โฏPMpodium presentation
"Introduction -
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The development of novel biocomposite formulations has significantly contributed to the biomedical field- specifically within translational and clinical applications. This study centres on the polyhydroxyalkanoates-based copolyester superfamily of materials, with a particular emphasis on the poly(3-hydroxybutyrate-co-4-hydroxybutyrate) [P(3HB-co-4HB)] copolymer as a novel... -
Boyadjiev, Alexander (Durham University )6/28/22, 4:30โฏPMpodium presentation
"INTRODUCTION:
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Extracellular matrix (ECM) protein is often used in cell culture to provide developmental cues for cells such as skin cells. This is especially important for the generation of epidermal models as without a dermal compartment the keratinocytes are reliant on the ECM coating to provide them with a foundation to adhere to and for pro-developmental cues. A major limitation of most... -
Vilaรงa-Faria, Helena (3Bโs Research Group, I3Bs โ Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine )6/28/22, 4:40โฏPMpodium presentation
"Introduction Tissue engineering (TE) is an interdisciplinary field that creates functional biologic substitutes for the repair of damaged tissues or organs. One major challenge when generating a functional TE model is its vascularization. Indeed, nutrient and oxygen supply, as well as metabolic waste products collection, are essential for the survival of the engineered tissue after...
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Zegwaart, Jan-Philip (Rousselot )6/28/22, 4:50โฏPMpodium presentation
Introduction: Due to their biocompatibility, biodegradability and cell-interactivity, gelatins are widely used in the biomedical and tissue engineering fields. Gelatin can be chemically crosslinked to originate constructs that are stable at body temperature. However, if modified gelatins cannot be produced with consistent molar mass and degree of modification (DoM), these advantageous...
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