GAMM2025

Session

S02: Biomechanics

S02

9 Apr 2025, 16:30

Lecture and Conference Centre

Conveners

S02: Biomechanics: S02.01

• Tim Ricken

S02: Biomechanics: S02.02

• Tim Ricken

Description

Section S02 will focus on numerical and experimental techniques to study the structure, function and evolution of biological systems for a broad spectrum of scales, i.e., addressing the cellular, tissue, organ, or organ system scale. The topics will focus on, but are not limited to, multiscale modelling, gait analysis, foot biomechanics, musculoskeletal and orthopedic biomechanics, remodeling, cardiovascular biomechanics, multiphase modeling of biological tissues, tumor growth modeling, transport oncophysics, nanomechanics of biological materials, nanomedicine, modeling of drug delivery, and image-based methods for assessing and interpreting clinical data.

14. A multifactorial approach for modelling vascular tone regulation: from molecular pathways through tissue response to systemic couplings

Michele Marino

09/04/2025, 16:30

The physiological behaviour of the cardiovascular system is highly affected by the mechanical response of arterial segments, that is in turn dependent from both tissue histological architecture and the contractile tone of smooth muscle cells. This work presents a comprehensive multi-scale and multi-field computational framework that accounts for: i) a lumped 1D description of the arterial...

15. Experimental and numerical characterisation of a viscoelastic material by unifying different time scales

Laura Ruhland

09/04/2025, 16:50

The mechanical characterisation of ultrasoft materials, such as brain tissue, over a wide time range is often limited by inconsistent responses when using different experimental techniques. These inconsistencies are predominantly attributable to the disparate testing conditions across the experiments. However, multi-modality tests are essential to calibrate a model that is applied to finite...

16. Multimodal mechanical characterization of spinal cord tissue

Rahul Gopalan Ramachandran

09/04/2025, 17:10

Traumatic spinal cord injury (SCI) in humans and many mammals is a non-regenerative condition that can lead to motor function loss and disability. Mechanical factors are increasingly recognized to be influencing spinal cord regeneration, yet accurate characterization of the mechanical behavior of spinal cord tissue is lacking. To address this gap, we employ a multimodal approach that combines...

17. PDE Framework for Tumor Invasion and Basement Membrane Dynamics: Application to Colorectal Cancer

Valentin Schmid

09/04/2025, 17:30

Colorectal cancer remains a major global health concern, and understanding the mechanisms of its progression is critical for advancing treatment and prevention strategies. In this presentation, we explore how PDE-based models can be applied to study tumor invasion and basement membrane dynamics, with an explicit focus on colorectal cancer. These models offer valuable insights into the...

18. A novel variational biofilm model for growth death and metabolism effects in coupled species evolution

Felix Klempt

09/04/2025, 17:50

Microorganisms are among the most successful forms of life on our planet. They are omnipresent, even in and around our bodies. For example, the oral cavity is home to hundreds of indigenous species of microorganisms that form complex communities known as biofilms. These biofilms can cause infections, particularly when foreign objects, such as implants, are introduced into a patient’s body....

19. Thickness field optimization of implants used in hernia treatment: comparison of materials with different mechanical properties

Szymon Kalinowski

09/04/2025, 18:10

The study presents an approach to the optimisation of the thickness field of surgical implants used in the treatment of abdominal hernias in humans, a medical condition with a high recurrence rate. Building upon previous research, this investigation aims to enhance the mechanical compatibility between native tissues of the human abdominal wall and implants reducing the likelihood of hernia...

20. Lower limb multibody model built in Artisynth for the use of coupled multibody-finite element simulations

Alexander Denk

10/04/2025, 08:30

Coupled multibody-finite element (MB-FE) simulations are state-of-the-art when characterizing a system's global dynamic behavior as well as local stress and strain phenomena due to deformation. In biomechanical research, this approach can address different hierarchical levels, including cellular, tissue, or organ system levels. Artisynth is an open-source Java-based biomechanical simulation...

21. Drift-Free Sagittal Angle Estimation in Outdoor Running Using IMUs: Application to Shank and Foot

Mehdi Ghiassi

10/04/2025, 08:50

Accurate motion capture is essential for the analysis and reproduction of human motion, particularly in dynamic activities like running. While traditional camera-based systems with retro-reflective markers remain the gold standard, they are limited by their reliance on controlled environments, restricted spatial range, and extensive setup requirements. Emerging alternatives utilizing inertial...

22. Finite element analysis of the human elbow joint

Julia Kasprzyk

10/04/2025, 09:10

Finite element analysis (FEA) can be a powerful tool for studying the biomechanical behavior of human tissues, offering insights into the performance of biological systems under various loading conditions. However, the finite element analysis has been applied sporadically to the elbow joint so far [1]. This presentation outlines the process of developing a finite element model of the human...

23. Finite Element Modelling of Impact Loads on the Human Head

Zechang Wang

10/04/2025, 09:30

This study is a follow-up to the study "Finite element modeling of concentrated impact loads on the masticatory muscles at the head" in GAMM 2024 Magdeburg. A human-subject study with collision loads is an appropriate methodology to determine thresholds for safe human-robot collaboration. However, the ethical requirements for such a study are very strict. Therefore, an available FE model has...

24. A new concept for embedding fibers in continua via level-sets

Thomas-Peter Fries

10/04/2025, 09:50

A concept for the embedding of homogenized fibers into bulk materials is proposed and generalized from [1, 2, 3]. Each fiber family in the bulk material is implied by a set of two level-set functions: The intersecting level sets of these function pairs are the continuously embedded fiber geometries. A mechanical model for the simultaneous consideration of all fibers in a large displacement,...

25. Characterization of the statistically inhomogeneous mesostructure of moso bamboo using image processing

Lukas Speichginger

10/04/2025, 10:10

Bamboo is characterized by a high growth rate and mechanical properties comparable to those of wood. Therefore, bamboo is of great interest as a sustainable building material while being an efficient CO2 absorber. The material has a hierarchical structure with heterogeneously distributed properties and correspondingly exhibits a strongly anisotropic behaviour [1,2]. Previous research has been...