Speaker
Description
In many therapeutic treatments, only a small fraction of the administered drug is absorbed, and a large part is wasted and released into the environment. Drug waste means economic loss and environmental risk. We present drug eluting materials with the unique property to self-produce biopharmaceuticals directly at the therapeutic site. The materials are hydrogels that host biofactories of natural therapeutics and maintain and regulate their productivity in-vivo over the long term. The biofactories produce and deliver the drug using energy sources from body fluids. We will present dynamic hydrogel compositions that can contain and control the proliferation and metabolic activity of encapsulated cell biofactories and can be processed into useful living devices with living therapeutic functions. We also present microarrays study multifactorial microbial responses in parallelized experimental formats. Self-replenishable drug eluting devices can deliver drugs continuously at the required concentration and can improve therapeutic outcome at zero-waste.
53381532697
