Speaker
Description
Gingival recession, a prevalent condition affecting the gum tissues, is characterized by the exposure of tooth root surfaces due to the displacement of the gingival margin. This presentation will emphasize the critical considerations in gingival tissue engineering leveraging on cells, biomaterials, and signaling factors. Successful tissue-engineered gingival constructs hinge on strategic choices such as cell sources, scaffold design, mechanical properties, and growth factor delivery. Recent biofabrication technologies like 3D bioprinting, electrospinning, and microfluidic organ-on-chip systems hold the potential to help elucidate precise control over cell arrangement, biomaterials, and signaling cues. These technologies empower the recapitulation of microphysiological features, enabling the development of gingival constructs that closely emulate the anatomical, physiological, and functional characteristics of native gingival tissues. Further, the parallels between the skin and gingival tissues will be highlighted, exploring the potential transfer of biofabrication approaches from skin tissue regeneration to gingival tissue engineering.