Conveners
S04 From single-cell to organoids:building advanced in vitro tissue models
- Daniel Nieto Garcia (Advanced Biofabrication Laboratory - DNIETO LAB, University of La Coruña, Spain)
- Joanna Idaszek (Warsaw University of Technology, Poland)
Photonics-based bioprinting technologies are redefining the frontiers of tissue engineering by enabling the fabrication of complex, multiscale biological constructs with unprecedented precision and speed. This talk will present some recent advancements in light-based bioprinting platforms—including a new technology named Holographic Optical Tweezers Bioprinting (HOTB), Multimaterial Volumetric...
Micro- and nano-scale technologies can have a significant impact on medicine and biology in the areas of cell manipulation, diagnostics, and monitoring. At the convergence of these new technologies and biology, we research for enabling solutions to real-world problems at the clinic. Emerging nanoscale and microfluidic technologies integrated with biofabrication methods in biology offer...
Introduction
One of the persistent challenges in the development of reliable in vitro tissue models is the inability to precisely and reproducibly control microarchitectures. This is especially critical for vascularized constructs, where network formation often relies on the stochastic self-assembly of randomly distributed cells, which leads to batch-to-batch variability, limited...
Understanding how spatial arrangements of diverse cell types within the tumor microenvironment (TME) influence cancer progression remains one of the foremost challenges in oncology. To address this, we have developed a suite of single-cell bioprinting technologies that enable engineering of tumor models with unprecedented spatial resolution in both two and three dimensions. Leveraging a...
Introduction: To date, no conjunctival spheroids have been reported, despite the conjunctiva’s vital role in maintaining ocular surface homeostasis and contributing to various ocular surface diseases. The conjunctiva is a dynamic, multi-cellular mucosal tissue that functions in barrier homeostasis, and tear film stabilization. However, physiologically relevant 3D in vitro models that replicate...
The field of biofabrication has made significant strides in the development of kidney models, offering promising solutions for addressing the growing demand for organ transplants and advancing our understanding of renal physiology and pathology. Biofabrication techniques, including 3D printing, enable the creation of models through sacrificial approaches. 3D printing supports the manufacture...
Bone is a dynamic tissue composed of osteoblasts, osteoclasts, and osteocytes, which continuously undergo bone formation and resorption through a process known as bone remodeling. This balance between formation and resorption is tightly regulated by intricate cell–cell interactions. Bone organoid research aims to replicate the characteristics of native bone tissue in vitro; however, the...
