Conveners
S05 Advancing 3D bioprinting through artificial intelligence
- Daniel Nieto Garcia (Advanced Biofabrication Laboratory - DNIETO LAB, University of La Coruรฑa, Spain)
- Nadina Usseglio (Advanced Biofabrication Laboratory - DNIETO LAB, University of La Coruรฑa, Spain)
AI-Enhanced Bioprinting: Intelligent Monitoring, Optimization and Virtual Prototyping.
Introduction
The integration of artificial intelligence (AI) and machine learning (ML) into bioprinting is revolutionizing the field of biofabrication. Traditionally based on experimental methods and manual trial-and-error, bioprinting is now evolving into a predictive and adaptive science. AI enables...
The manipulation of three-dimensional (3D) cellular structures such
as organoids and spheroids plays a central role in modern biomedical
applications, including tissue engineering, drug screening, and disease
modeling. However, the accurate and reproducible transfer of these fragile
structures remains a technical bottleneck. Manual handling is limited by user
variability, lacks...
Biointelligence is an emerging paradigm in manufacturing that integrates bio-inspired principles and biological components with hardware and software to create intelligent, adaptive, and biologically interactive production systems. Two-Photon Polymerization (2PP) is an Additive Manufacturing (AM) technology that supports Biointelligence by enabling the fabrication of high-resolution,...
The work concerns the development and characterization of novel water-soluble photoinitiators based on benzoin derivatives for the initiation of radical photopolymerization processes in aqueous media. The main objective of the study was to create compounds that combine high performance, good water solubility, low cellular toxicity and spectral compatibility with commonly used UV and VIS light...
In 3D extrusion bioprinting, precise and reliable material deposition is essential for fabricating consistent tissue constructs. However, elastic components like disposable syringes and flexible tubing introduce unpredictable deformation and backlash, decoupling piston movement from actual material extrusion. The challenge is further amplified with high-viscosity, non-Newtonian bioinks, whose...
Spherical-based architected scaffolds have gained increased interest in tissue engineering (TE) due to their curved architecture, which inherently reduces stress concentrations and enables controlled mechanical performance. However, designing and optimising such architectures remains challenging because of the intricate relationship between their structural and functional properties.
This...
The fabrication of large, perfusable tissue constructs remains a major challenge in regenerative medicine due to the complexity of translating vascular networks across multiple scales. Here, we present an agentic generative AI (GenAI) platform capable of autonomously generating STL files for bioprinting macro-to-millimeter-scale architectures that are subsequently colonized by self-organizing...
Ourobionics is pioneering a transformative paradigm in regenerative medicine and tissue engineering through the development of a predictive biofabrication platform that integrates 3D Bio-Electrospraying (3D-BES), 3D Cell-Electrospinning (3D-CE) to create complex human tissue with biomarker biosensors connected to generative artificial intelligence (AI).
Unlike conventional extrusion-based...
