2025 International Conference on Biofabrication

Session

S06 Advancing Biofabrication for Regenerative Medicine: From Innovation to Clinical Translation

15 Sept 2025, 11:00

Kisielewski

Conveners

S06 Advancing Biofabrication for Regenerative Medicine: From Innovation to Clinical Translation

• Axel Guenther (University of Toronto)
• Andreea Ioana Dinu (National University of Science and Technology Politehnica Bucharest)

438. First use of UV-light activated biomaterial in atraumatic hernia repair in patients

Mirosława El Fray (Warsaw University of Technology)

15/09/2025, 11:00

invited lecture

Introduction
Surgical mesh implantation represents the current standard of care in inguinal hernia repair; however, conventional fixation using sutures is associated with risks of chronic neuralgia-type pain and local tissue irritation. Alternative fixation methods employing fibrin or cyanoacrylate-based adhesives have been introduced, but each presents inherent limitations in terms of...

410. Enhancing Osteoarthritis Therapy through RNA Delivery and AI Diagnostics: A Comprehensive Strategy for Early Detection and Targeted Treatment

Chandrashish Roy (Indian Institute of Technology Delhi)

15/09/2025, 11:20

podium presentation

Introduction
Osteoarthritis (OA) is a debilitating joint disease characterized by the progressive degradation of cartilage, leading to pain, stiffness, and limited mobility. Early detection and effective treatment are critical to improving patient outcomes. In this study, we introduce a combined method that uses a new way to deliver RNA with Silk Fibroin (SF) hydrogels and artificial...

378. Hybrid Bioprinted Dressings for Deep Wound Repair: Harnessing Methacrylated Hyaluronic Acid and Recombinant Proteins for Enhanced Healing in a Porcine Model

Kinga Rusinek (Polbionica Inc.)

15/09/2025, 11:30

podium presentation

Introduction:. An innovative approach combining pre-crosslinked methacrylated hyaluronic acid (HAPrime) with hybrid recombinant proteins was developed to create highly effective dressings for deep wound treatment. Treating deep wounds in animals, particularly pigs, remains a significant challenge due to risk of infection and delayed tissue regeneration. Emerging regenerative strategies, such...

368. Biofabricated auricular cartilage grafts for clinical translation

Philipp Fisch (ETH Zürich)

15/09/2025, 11:40

podium presentation

Introduction: Tissue engineering has the potential to revolutionize the treatment of microtia, the congenital malformation of the external ear. Patient-specific auricular grafts could be engineered from a small biopsy of approximately 5 mg, eliminating the need for rib cartilage, and provide better aesthetics through biofabrication techniques, resulting in a real, natural ear. However, despite...

288. Towards Clinical Translation: Treatment of Volumetric Muscle Loss with Mechanically Reinforced Engineered Tissues

Eva Schaetzlein (Technical University of Darmstadt)

15/09/2025, 11:50

podium presentation

Introduction
Volumetric muscle loss due to trauma often exceeds the body’s intrinsic regenerative capacity. The gold standard of treatment with autologous transplants carries the significant drawbacks of donor site morbidity and limited availability. Although current tissue-engineered products offer potential, they require improvements in terms of shape fidelity, surgical handling, transport,...

411. Advancing Bone Regeneration: 3D Printed β-TCP Implants via LCM in Preclinical Evaluation

Lukasz Witek (NYU College of Dentistry)

15/09/2025, 12:00

podium presentation

Clinical application of beta-tricalcium phosphate (β-TCP) has been limited by lack of bone infiltration within its bulk form. Lithography-based ceramic manufacturing (LCM), a novel additive manufacturing (AM) technique, leverages photopolymerization to create β-TCP structures with higher feature resolution and surface quality than traditional techniques. This modality allows for a more...

387. 3D BioPrinting: Organ-On-Chips models for drug screening applied to diabetic foot ulcer

Pompeo Marco Gaudiosi (Politecnico di Torino)

15/09/2025, 12:10

podium presentation

Type 1 Diabetes Mellitus (T1DM) is an autoimmune condition resulting in the destruction of insulin-producing beta cells, leading to chronic hyperglycemia and accumulation of advanced glycation end products (AGEs). These factors contribute to serious complications such as diabetic foot ulcers (DFUs) (1-2), which result from chronic inflammation, vascular damage, and neuropathy. Despite their...

233. Next-Generation Hemodialysis Membranes: Composites Modified with Nanoparticles for Improved Performance

Marta Woźniak-Budych (Adam Mickiewicz University, NanoBioMedical Centre)

15/09/2025, 12:20

T-PS06 Advancing Biofabrication for Regenerative Medicine: From Innovation to Clinical Translation

podium presentation

Introduction
The performance of hemodialysis membranes depends on uremic toxin clearance, biocompatibility, mechanical properties, and the ultrafiltration characteristics of the hemodialyzer [1]. The clearance rate can be controlled by membrane properties, such as thickness, morphology, and pore size, as well as the surface properties of the membrane [2].
Methods
Novel hemodialysis...