Conveners
S07 Advancing Biofabrication Methods for Macro-Scale Tissue Engineering
- Joรฃo Maia (Universidade de Aveiro)
- Philipp Fisch (ETH Zรผrich)
Bioinspired engineered microenvironments provide cells with a holistic โinstructive nicheโ that offers the adequate entourage for cellular control both in space and time. Such approaches are important to design hierarchical constructs with applicability, for example, in tissue engineering or in the development of in vitro models for drug screening. We have been proposing strategies of...
Collagen-based biomaterials have gained increasing attention in regenerative medicine and nutraceutical applications. This study integrates three complementary approaches: the investigation of collagenous biopolymers from marine spongin, the development of bioinks derived from decellularized collagen-rich extracellular matrix (dECM) of the porcine meniscus for 3D bioprinting, and the creation...
Introduction
Bioprinting for Tissue Engineered Advance Therapeutic Medicinal Products (TE-ATMPs) recently gaining ground aiming to regenerate defects and restoration of damaged tissues for bone tissue engineering solutions. The efficiency of TE-ATMPs is related to high cell density constructs as obtained via organoid bioassemblies. This has been convincingly demonstrated for engineered...
Introduction
Materials capable of undergoing shape transformations in response to external stimuli offer significant advantages for a range of applications, including biomedical implants, soft robotics, and medical devices.[1] Microgel-based scaffolds have recently gained attention among these applications due to their interstitial microscale voids, which make them superior in oxygen and...
Cardiovascular diseases (CVDs) remain the leading cause of death globally, with myocardial infarction (MI) as a major contributor. Traditional 2D cultures and animal models fail to recapitulate the native electromechanical properties and pathological responses of the human myocardium. Recent advancements in human-induced pluripotent stem cell (hiPSC) technology and 3D bioprinting have enabled...
Exploring the natural availability and intrinsic bioactivity of blood-derived proteins opens new avenues for fabricating bioactive and personalized constructs for biomedical applications. However, these biomaterials lack suitable viscoelastic proprieties for 3D printing of complex tissue structures. Ink engineering is progressively being utilized to advance the printability of better...
Introduction: Materials science and regenerative medicine are promising avenues for production of tissue-engineered vascular grafts (TEVGs) with biomimetic extracellular matrices (ECMs) [1โ3]. However, many TEVGs exhibit poor mechanical compliance [4,5], with studies often overlooking the complex role of ECMs and mechanics. Here, highly compliant TEVGs were cultured in pulsatile bioreactors...
