Conveners
S11b Biofabrication of Soft Tissues
- Aida Fadakarsarkandi (The University of Birmingham)
- Vijayavenkataraman Sanjairaj (New York University Abu Dhabi)
The recent development of bioengineering enables to create human tissues by integrating various native microenvironments, including tissue-specific cells, biochemical and biophysical cues. A significant transition of 3D bioprinting technology into the biomedical field helps to improve the function of engineered tissues by recapitulating physiologically relevant geometry, complexity, and...
Skin is the largest organ of the human body acting as a barrier against physical and chemical stimuli. It is well known that exposure to solar UV rays, UVA and UVB, damages its structure and ages prematurely the skin (a phenomenon called photoaging). In the last decades, three-dimensional (3D) in vitro models were considered to test novel cosmetic and pharmaceutical products against...
3D multicellular models provide valuable platforms for tissue regeneration, disease modeling, and biomaterial evaluation. However, the recreation of complex stratified systems that combine different tissue types and pathophysiological conditions remains challenging. In this work, we developed a multilayer construct integrating skin, muscle, and bone components using digital light processing...
Digital Light Processing (DLP) is a 3D printing method that offers enhanced precision, quicker print times, increased throughput, and better cell viability by minimizing shear stress compared to extrusion-based bioprinting, which depends on mechanical nozzle deposition and tends to be slower with lower resolution. These advantages make it particularly well-suited for fabricating complex tissue...
Introduction
The field of regenerative medicine increasingly demands scalable, patient-specific soft tissue constructs. While hydrogel-based bioprinting provides a favorable environment for cell viability, it often lacks mechanical integrity - especially critical for replicating the elastic nature of soft tissues. Traditional scaffold-integrated bioprinting has improved structural support but...
One of the most innovative areas of 3D printing development is bioprinting, the creation of biological structures using living cells and bioinks. This technology enables the production of tissue scaffolds that can serve as templates for regenerative cells. These applications include printing skin and cartilage, as well as preliminary attempts at printing organs such as kidneys, liver, and...
There is much interest in biofabrication of tubular constructs for repair and regeneration of several tissues in the human body, such as blood vessels, nerve conduits, gastro-intestinal tract, and bile duct, among others. The rapidly growing field of additive manufacturing and 3D printing technologies is offering new routes for the processing of biomaterials for the fabrication of implants and...
Cardiovascular surgery continues to face a shortage of suitable biomaterials for full-vessel bypass procedures and vascular patch repair. Current materials exhibit several limitations, including poor patency in small-diameter vessels, limited remodeling capacity, and a high risk of thrombosis [1]. While PLCL (poly(L-lactide-co-ฮต-caprolactone)) nanofiber sheets are biodegradable over several...
