Conveners
S12 Biofabrication of Tissue Interfaces: Bridging the Gap Between Structure and Function
- Andrew Daly (University of Galway)
- Felipe Mateus Franco (York University)
Porous scaffolds are fundamental components in the field of tissue engineering and regenerative medicine, serving as essential frameworks that support and guide the growth, attachment, and proliferation of cells. These scaffolds mimic the natural extracellular matrix, providing a three-dimensional environment conducive to tissue development. One of the most critical features of these scaffolds...
Introduction
Although cellularized biomaterial constructs have significantly advanced tissue repair and regenerative medicine, their clinical translation remains limited due to labor-intensive preparation processes and inadequate shelf-life. Therefore, creating modular, shelf-ready, cellularized products with long-term preservation capability and immediate clinical utility is critically...
Introduction: Retinal pathologies affect more than 350 million people worldwide yearly, impairing visual acuity and quality of life [1-3]. Despite therapy procedures for these pathologies already existing, more effective and patient-friendly ones are the subject of research. Animal models, mainly used in this field, are expensive, time-consuming and present regulatory issues [4]. On the other...
Unlocking natural-based multimaterial 3D printing by engineering the nanocomposite organic/inorganic interface
J.R. Maia1, Daniel S. Fidalgo2, Marco Parente2, R. Sobreiro-Almeida1, J. F. Mano1
1 Department of Chemistry, CICECO – Aveiro Institute of Materials, University of Aveiro, 3810-193, Aveiro, Portugal
2 Institute of Science and Innovation in Mechanical and Industrial Engineering...
Introduction:
Deep vat printing (DVP) techniques, such as tomographic (Figure 1A) and filamented light (FLight) (Figure 1B) printing, have advanced biofabrication by enabling high-resolution, layer-free fabrications at unprecedented speeds[1]. Despite, collagen being the most widely used matrix in tissue engineering, its compatibility with DVP remained unexplored. Within this work, we...
The structural alignment of cells is a hallmark of functional neural and neuromuscular tissues. However, replicating this anisotropic architecture in engineered three-dimensional (3D) constructs remains a significant challenge in tissue engineering. In this study, we introduce a cryobioprinting strategy capable of fabricating aligned, multi-cell-type scaffolds for modeling neural tissues and...
Background:
The global rise of skin infections, exacerbated by antibiotic-resistant bacteria, is nowadays a great challenge to healthcare. Traditional treatments are increasingly losing their potential, leading to severe impacts on patient quality of life and survival rates. Consequently, many efforts are made to develop innovative antibacterial therapies. To test this new strategies,...
The blood–brain barrier (BBB) is a highly specialized neurovascular interface that regulates the selective exchange of molecules between the bloodstream and the central nervous system, playing a critical role in maintaining brain homeostasis (Cruz et al., 2023). Despite advances in in vitro modeling, many existing BBB models lack the structural and functional complexity necessary to fully...
