2025 International Conference on Biofabrication

Session

S12 Biofabrication of Tissue Interfaces: Bridging the Gap Between Structure and Function

16 Sept 2025, 15:30

Rudniew

Conveners

S12 Biofabrication of Tissue Interfaces: Bridging the Gap Between Structure and Function

• Andrew Daly (University of Galway)
• Felipe Mateus Franco (York University)

495. Programming degradation of sacrificial microgels to direct cellular function

Khoon Lim (University of Sydney)

16/09/2025, 15:30

invited lecture

Porous scaffolds are fundamental components in the field of tissue engineering and regenerative medicine, serving as essential frameworks that support and guide the growth, attachment, and proliferation of cells. These scaffolds mimic the natural extracellular matrix, providing a three-dimensional environment conducive to tissue development. One of the most critical features of these scaffolds...

373. Long-term Cryopreserved Interface-incorporated Microtissues: An Injectable and Printable Solution for Shelf-ready Regenerative Therapies

Chuqian Wang (Tsinghua University)

16/09/2025, 15:50

podium presentation

Introduction
Although cellularized biomaterial constructs have significantly advanced tissue repair and regenerative medicine, their clinical translation remains limited due to labor-intensive preparation processes and inadequate shelf-life. Therefore, creating modular, shelf-ready, cellularized products with long-term preservation capability and immediate clinical utility is critically...

324. An innovative 3D eye in vitro model as an experimental platform for theragnostic: the Tuscany Health Ecosystem approach

Gabriele Maria Fortunato (University of Pisa)

16/09/2025, 16:00

podium presentation

Introduction: Retinal pathologies affect more than 350 million people worldwide yearly, impairing visual acuity and quality of life [1-3]. Despite therapy procedures for these pathologies already existing, more effective and patient-friendly ones are the subject of research. Animal models, mainly used in this field, are expensive, time-consuming and present regulatory issues [4]. On the other...

249. Unlocking natural-based multimaterial 3D printing by engineering the nanocomposite organic/inorganic interface

João Rocha Maia (University of Aveiro)

16/09/2025, 16:10

podium presentation

Unlocking natural-based multimaterial 3D printing by engineering the nanocomposite organic/inorganic interface

J.R. Maia1, Daniel S. Fidalgo2, Marco Parente2, R. Sobreiro-Almeida1, J. F. Mano1
1 Department of Chemistry, CICECO – Aveiro Institute of Materials, University of Aveiro, 3810-193, Aveiro, Portugal
2 Institute of Science and Innovation in Mechanical and Industrial Engineering...

370. Rapid deep vat printing of tissue interfaces using photoclickable collagen-based bioresins

Michael Winkelbauer (ETH Zürich)

16/09/2025, 16:20

podium presentation

Introduction:
Deep vat printing (DVP) techniques, such as tomographic (Figure 1A) and filamented light (FLight) (Figure 1B) printing, have advanced biofabrication by enabling high-resolution, layer-free fabrications at unprecedented speeds[1]. Despite, collagen being the most widely used matrix in tissue engineering, its compatibility with DVP remained unexplored. Within this work, we...

277. Hyaluronic Acid-Based Bioink for Cryobioprinting of Anisotropic Neural and Neuromuscular Tissue Constructs

Andrea Andolfi (Harvard Medical School)

16/09/2025, 16:30

podium presentation

The structural alignment of cells is a hallmark of functional neural and neuromuscular tissues. However, replicating this anisotropic architecture in engineered three-dimensional (3D) constructs remains a significant challenge in tissue engineering. In this study, we introduce a cryobioprinting strategy capable of fabricating aligned, multi-cell-type scaffolds for modeling neural tissues and...

429. Broadly accessible 3D in vitro skin model as a comprehensive platform for antibacterial therapies screening

Raquel Cue-Lopez (Politecnico di Torino)

16/09/2025, 16:40

podium presentation

Background:

The global rise of skin infections, exacerbated by antibiotic-resistant bacteria, is nowadays a great challenge to healthcare. Traditional treatments are increasingly losing their potential, leading to severe impacts on patient quality of life and survival rates. Consequently, many efforts are made to develop innovative antibacterial therapies. To test this new strategies,...

413. Embedded 3D Bioprinting of Perfusable Endothelialized Microchannels for Blood-Brain Barrier Model

Bahattin Koc (Sabanci University)

16/09/2025, 16:50

podium presentation

The blood–brain barrier (BBB) is a highly specialized neurovascular interface that regulates the selective exchange of molecules between the bloodstream and the central nervous system, playing a critical role in maintaining brain homeostasis (Cruz et al., 2023). Despite advances in in vitro modeling, many existing BBB models lack the structural and functional complexity necessary to fully...