Conveners
S19 Complex architectures and non-planar approaches in Biofabrication
- Pasquale Posabella (Warsaw University of Technology)
- Pierpaolo Fucile (MERLN Institute for Technology-Inspired Regenerative Medicine)
The functional and sensory augmentation of living structures, such as human skin and plant epidermis, with electronics can be used to create platforms for health management and environmental monitoring. Ideally, such bioelectronic interfaces should not obstruct the inherent sensations and physiological changes of their hosts. The full life cycle of the interfaces should also be designed to...
The first publication that presented embedded 3D printing was titled "Omnidirectional Printing". This term elegantly captured the ability to write non-planar and freeform filaments. However, the use of a support bath requires a physical bath to hold the gel, and allows entry only from the top. A truly omnidirectional method of 3D printing would enable printheads to construct parts from all...
Introduction: To this date, Melt Electrowriting (MEW) is primarily done on flat collectors for tissue engineering (TE) applications. There are no flat geometries in the body, so it is crucial to find ways to fabricate out-of-plane scaffolds that better conform to the shape of the targeted tissues. 6-axis robots have been used in MEW to move the printhead around a static collector for the...
Tissue Engineering (TE) and Regenerative Medicine (RM) seeks to mimic the complex structure and functionality of natural tissues, where directionally-dependent properties and negative Poisson's ratio behaviors are essential to guide cell migration and activity, ultimately leading to influencing tissue regeneration. These characteristics are fundamentally linked to fiber orientation and...
The advancement of disease modeling and drug testing has been consistently limited by the shortcomings of conventional in vitro and in vivo models, which often fail to accurately replicate the complex microenvironment of human tissues. To address this issue, our study introduces an innovative in vivo-mimicking three-dimensional human colon model that reproduces the structural, mechanical,...
Introduction
Animal models have been the gold standard for testing chemotherapeutic drugs, but less than 5 percent of drugs passed clinical trials between 2000 and 2015 [1]. Furthermore, regulatory agencies are mandating the reduction of animal testing [2]. We propose a tumor-on-a-chip model facilitated by multiphoton lithography (MPL), a high-resolution 3D printing technology that enables...
Introduction
Xolography is a scalable volumetric 3D printing technology[1] enabling rapid and precise fabrication of complex hydrogel structures[2]. Its recent adaptation for bioprinting has opened exciting possibilities for tissue engineering and regenerative medicine[3]. Yet, standard bioresins like GelMA have shown limited reactivity—a challenge recently addressed through smart formulation...
