Conveners
S22b Bioprinting From Earth to Space
- Joรฃo F. Mano (Universidade de Aveiro)
- Marina Volpi (Warsaw University of Technology, Poland)
In the last decades crewed space research was limited to the International Space Station (ISS) from where a fast return to Earth in case of severe health issues of the astronauts always is possible. This will not be the case anymore in the upcoming space missions to Moon and finally maybe to Mars. As a consequence, health care support mechanisms must be developed that are completely...
Introduction: Experiments on the International Space Station (ISS) involve extremely high costs, often amounting to several million euros. These expenses primarily arise from transportation costs and the valuable time required from astronauts. Additionally, long-term missions to the Moon or Mars face significant challenges due to limited resource availability.1 Due to the high costs of...
Introduction
Microgravity provides a unique environment for advancing tissue engineering and biofabrication by eliminating gravitational constraints such as sedimentation, buoyancy, and hydrostatic pressure gradients. These factors enable 3D bioprinting of tissue and organ constructs of more complex geometries in three dimensions, offering structural and functional fidelity that is difficult...
Type I collagen, is the central component of the extracellular matrix (ECM) and its use in the context of regenerative medicine is expected to mark an important turning point towards the use of biomimetic materials in regenerative medicine. Collagen provides mechanical support and biological cues for cellular adhesion and proliferation making it an ideal choice for fabricating biomimetic...
Implantable peripheral neural interfaces (PNIs) have demonstrated considerable versatility by facilitating direct access to targeted nerves with high signal specificity, thereby enabling both the acquisition of physiological information through electrical recording and the modulation of organ function via controlled electrical stimulation. However, the long-term performance of most implantable...
Invasion of cancer cells into surrounding tissue represents the first step of metastasis and is strongly controlled by the tumor microenvironment. In breast cancer, adiposeโderived stromal cells (ASCs) from adjacent adipose tissue are increasingly recognized as important regulators of this process, but the underlying mechanisms remain unclear. While bioprinting offers unique advantages for...
Biofabrication technologies have been largely developed to address medical needs, with the ultimate goal of enabling regenerative therapies. However, in our effort to advance toward that goal, we often generate tools, insights, and applications that reveal their own value in complementary, non-medical domains.
In this keynote, I will share how our work in chaotic bioprintingโoriginally...
Small-diameter vascular conduits for the treatment of cardiovascular diseases are in high demand. Bioprinting a patient-specific blood vessel is an attractive alternative, however, the inferior mechanical properties of cell-laden hydrogels is a major drawback. Here, we present a combined electrospinning and bioprinting technique in which electrospun nanofibers and cell-laden hydrogels are used...
