Conveners
S36 Support baths for embedded bioprinting of biomimetic tissues and in vitro models
- Daniel Kelly (Trinity College Dublin)
- Andrew Daly (University of Galway)
Bioprinting with high cell-density bioinks holds great promise for cellular condensation-based tissue engineering and regenerative medicine. However, achieving precise control over complex tissue structures and organization using high cell-density bioinks remains a significant challenge. Here, we introduce a novel approach for fabricating tissue-specific constructs by directly assembling high...
Current clinical approaches for tendon injuries and disorders remain limited, often leading to suboptimal outcomes such as poor healing and high reinjury rates. Tissue engineering holds promise as an alternative, yet the unique characteristics of tendon tissueโits complex hierarchical architecture, distinct biomechanical properties, sensitivity to mechanical stimuli, and inherently low...
Constructing an in vitro vascularized liver tissue model that mimics the human liver plays a key role in promoting cell growth and biomimetic physiological heterogeneous structures and cellular microenvironments. However, the layer-by-layer printing method is greatly limited by the rheological properties of the bioink, making it difficult to form complex three-dimensional vascular structures...
The development of innovative bioinks and bioprinting strategies is critical for advancing tissue engineering and regenerative medicine. Collagen, a major structural protein in the extracellular matrix, is widely used in bioink formulations due to its biocompatibility and ability to support cell growth and differentiation. However, a primary challenge with collagen-based inks is their low...
Introduction
3D-bioprinting for cartilage tissue engineering can provide controlled cell localization and complex tissue shapes fabrication to meet clinical needs. Extrusion-based 3D-bioprinting has demonstrated resolution limitations owing to surface tension effects. Therefore, confined printing techniques such as Freeform Reversible Embedding of Suspended Hydrogels (FRESH) have been...
Engineering functional articular cartilage (AC) remains a challenging goal in tissue engineering. Since the function of AC is derived from its depth-dependent organization, the field has typically focused on developing multilayered scaffolds that mimic specific zonal aspects of the native tissue. Scaffolds have succeeded in recapitulating some aspects of native AC, however, they have generally...
Introduction
Pulmonary fibrosis (PF) is a debilitating disease with a poor prognosis, often linked to long-term exposure to harmful substances. Understanding the role of pollutants in PF onset requires sophisticated in vitro models capable of replicating lung physiology and pathology. In this contribution we present the realisation of an innovative approach based on new materials and 3D...
