Conveners
S22d General Symposia
- David Dean (University of Wisconsin-Madison)
- Jeroen Leijten (University Twente)
Biofabrication is an emerging field of engineering aimed at creating tissues and tissue-like structures. A key technology in biofabrication is 3D bioprinting, which utilizes methods of precise layer-by-layer deposition of cell-containing bioingredients to form active 3D structures. While 3D bioprinting allows for the creation of some biologically relevant shapes and structures, its reliance on...
Development and Characterization of Alginate-Based Bioinks incorporating Nicotiana tabacum Cells for Bioprinting
Kira Schnellbรคcher1, Adrian Rehn1, Robin Maatz1, Andreas Blaeser1
1 Technical University Darmstadt, IDD, Germany (schnellbaecher@idd.tu-darmstadt.de, blaeser@idd.tu-darmstadt.de)
Plant cells are valuable for producing various molecules due to their secondary metabolism [1]....
Physiologically relevant in vitro models of connective tissues are critical for advancing tissue engineering and disease modeling. However, replicating the hierarchical organization and extracellular matrix (ECM) richness of native stromal environments remains a significant challenge. Traditional scaffold-based approaches often lack the resolution and biological complexity to support proper...
INTRODUCTION
Skin possesses a complex structure with diverse components. The epidermis consists of tightly packed epithelial cells, while dermis contain fibroblasts, blood vessels, sensory neurons, immune cells, and hair follicles. Both in vitro and in vivo models serve as useful tools for studying skin biology and uncovering the cellular and molecular processes involved in degenerative skin...
Bovine meat is one of the preferred sources of protein around the world due to its remarkable nature. Meat exhibits a high density of high-quality protein, is well-balanced in essential amino acids, and has a very distinctive set of textural and flavor attributes. However, traditional methods of meat production have been heavily criticized for their poor sustainability, particularly in terms...
Single cell printing techniques are extremely valuable for the precise and controlled construction of tissue precursors. However, existing methods for printing single cells are subject to rheological restrictions. In addition, the high resolution required for printing individual cells conflicts with the desire for time-efficient construction of 3D structures.
This work addresses the question...
INTRODUCTION: The integration of biomaterials with living cells presents a critical bottleneck in the field of tissue engineering and regenerative medicine. Despite the rapid progress in biofabrication technologies, designing functional and biologically relevant tissue constructs that mimic native organ complexity remains challenging. Here, we assembled semi-synthetic liver-like tissues using...
Abstract
The tumor microenvironment is characterized by an elevated hydrogen ion concentration, which is the result of increased cellular metabolic demand and altered perfusion, e.g., oxygen availability or acidic metabolic waste products. The acidity of the tumour microenvironment, which is spatially and temporally heterogeneous, affects cancer initiation and progression, but also the...
