Conveners
Rapid Fire Talks 2
- Nehar Celikkin (Institute of Physical Chemistry (PAN))
Introduction
Cartilage defects pose significant challenges in terms of healing. Current treatments have limitations in size, availability, or durability.[1,2] Biofabrication aims to restore tissue functionality by placing biological active components in a pre-defined 3D organization, typically using soft hydrogels for cell preferences.[3] These hydrogels can be mechanically reinforced with...
Introduction
Osteoarthritis (OA) is a degenerative disease affecting osteochondral (OC) tissue, leading to pain and joint dysfunction. Current treatments are often limited by availability, efficacy, and cost, highlighting the need for innovative therapeutic approaches. To address this challenge, we propose a novel tool EndoFLight, an advanced in situ 3D bioprinting platform designed for...
Gelatin Methacryloyl (GelMA) attractes considerable research attention as an important structural
component for bioinks.1 The synthesis of GelMA involves the methacrylation of gelatin, wherein methacryl groups are covalently bonded to the amino groups of lysine residues. The degree of methacrylation (DM) is a critical parameter that significantly affects the physicochemical properties of...
Introduction
Over the past few decades, extensive research has been actively conducted for the fabrication of human tissues to, amongst many applications, understand the effects of a wide range of chemicals on human health and the environment (1). Thus, the need for the development of innovative assessment tools that provide reliable results in identifying and regulating the risks of...
HYCON: A Hydrogel-based Conformable Electrode Array for Noninvasive Electrophysiological Recording of Brain Organoids
Introduction:
Brain organoids have become an essential tool for modeling human brain development, neurological disorders, and therapeutic interventions. However, designing reliable interfaces for these 3D, delicate structures remains a key challenge. Current...
Introduction:
Replicating physiologically relevant tissue environments in vitro requires both sophisticated biological design and reliable scalable fabrication. Current approaches often rely on complex biofabrication methods such as stereolithography (SLA) and melt electrowriting (MEW), which are time-intensive, laborious, and lack reproducibility at scale [1,2]. To overcome these...
