2025 International Conference on Biofabrication

Session

Poster Session I

14 Sept 2025, 17:30

Poster Area

Conveners

Poster Session I: Poster Exhibition

• Carmelo De Maria (University of Pisa)
• Marco Costantini (Institute of Physical Chemistry Polish Academy of Sciences)

Poster Session I: Poster Exhibition

• Marco Costantini (Institute of Physical Chemistry Polish Academy of Sciences)
• Carmelo De Maria (University of Pisa)

Description

posters are on display whole day on Sunday and Monday

214. 3D bioprinting of methacrylated xanthan/halloysite nanotubes for wound healing apllications

Mădălina Cristina Nicolae (National University of Science and Technology POLITEHNICA Bucharest)

15/09/2025, 10:30

T-PS11 Biofabrication of soft tissues

poster

INTRODUCTION
The skin has restricted regeneration potential in the presence of certain illnesses. In certain
circumstances, the using of specific treatments is strongly recommended in order to improve the
wound healing process. Polysaccharide-based biomaterials exhibit a high potential for wound healing
because this category maintains wound hydration, allows gas exchange and absorbs...

101. 3D Bioprinted Papillary Dermis Models for Investigating the Impact of Aging on Epidermal Development

Gabriel Baldissera (Yale University, Department of Pathology)

15/09/2025, 10:35

T-PS13 Biofabrication strategies for engineering microarchitectural complexity

poster

The dermal-epidermal junction is critical in maintaining skin homeostasis, providing mechanical support, and facilitating nutrient exchange. One of the key features of this interface is the papillary dermis, which is characterized by a series of undulations that increase surface area for diffusion between dermal and epidermal compartments. During aging, these undulations flatten, resulting in...

163. 3D electrospun-based hydrogels for skin regeneration

Nikoletta Varha (Polytechnic of Leiria)

15/09/2025, 10:40

T-PS13 Biofabrication strategies for engineering microarchitectural complexity

poster

Introduction
In Europe, around 60 million people have diabetes, and approximately 15% will develop diabetic foot ulcers (DFUs), with annual treatment costs of €4–6 billion [1]. Neuropathy hinders early wound detection, complicating DFU management [2]. Electrospun structures mimic the skin’s extracellular matrix but their 2D nature limits full regeneration [3]. This study proposes to create a...

119. 3D Optical Coherence Tomography (OCT) Imaging as a Tool for Quality Assessment of Multi-Material Volumetric Printed Vascular Models

Isabel Geroneit (Department for Functional Materials in Medicine and Dentistry, University of Würzburg)

15/09/2025, 10:45

T-PS07 Advancing Biofabrication Methods for Macro-Scale Tissue Engineering

poster

Introduction: The development of biofabrication requires reliable and standardized methods for quantifying a wide range of printing techniques and tissue models to ensure a successful translation into medical applications. With the rise of convergence and the integration of multiple materials, printing processes are becoming increasingly complex, posing challenges for structural analysis....

221. 3D PRINTED BIO-BASED SCAFFOLD FOR CARTILAGE REGENERATION

Dorota Kołbuk-Konieczny (Polish Academy of Sciences)

15/09/2025, 10:50

T-PS08 Biofabrication for cartilage regeneration and joint preservation

poster

Cartilage injuries remain a major clinical challenge due to the tissue’s limited self-healing capacity. Standard treatments, such as microfracture or autologous chondrocyte implantation, are often insufficient in restoring full function and structure of damaged cartilage. In this study, we present the SmartPiezo scaffold - a novel 3D printed, bio-based, and biodegradable construct designed...

550. 3D-printed Chitosan-Agarose scaffolds for biomedical applications: An in-vitro comparative study of the oxide nanoparticles doped structures

Amir Hashemi (Mendel University in Brno)

15/09/2025, 10:55

T-PS06 Advancing Biofabrication for Regenerative Medicine: From Innovation to Clinical Translation

poster

Introduction
Large bone defects caused by trauma or surgical resection often require scaffolds that both promote regeneration and prevent bacterial infection. Chitosan–agarose (CA) hydrogels are biocompatible and printable, but their limited mechanical strength and weak antibacterial capacity remain challenges. Incorporating metal oxide nanoparticles (NPs) such as ZnO, MgO, and CaO offers a...

211. 3D-Printed Double-nanostructured Scaffolds for Osteochondral Bone Defect Repair

Andreea Ioana Dinu (National University of Science and Technology Politehnica Bucharest)

15/09/2025, 11:00

T-PS07 Advancing Biofabrication Methods for Macro-Scale Tissue Engineering

poster

Introduction
Osteochondral defects involve damage to both the articular cartilage and the underlying subchondral bone, often resulting in joint instability and risk of osteoarthritic degeneration [1]. Recent research in treating such complex joint lesions focuses on developing 3D porous biomaterials, engineered with precise size and shape specifications through additive manufacturing...

215. 3D-Printable Gelatin-Derivatives for the Design of In Vitro Diabetic Skin Models

Andrea Cosola (Politecnico di Torino)

15/09/2025, 11:05

T-PS11 Biofabrication of soft tissues

poster

Diabetes mellitus (DM) is a complex metabolic disease characterized by impaired glucose metabolism (hyperglycemia), leading to severe and long-term complications, such as kidney failure, stroke, peripheral neuropathy, nephropathy and, above all, foot ulcers.
In the last years, 2D in-vitro cell culture systems and 3D in-vivo animal models have been particularly useful in understanding the...

226. 3D printed scaffolds incorporated autologous growth factor for bone tissue engineering

Akhilesh Agrawal (Indian Institute of Science)

15/09/2025, 11:10

T-PS06 Advancing Biofabrication for Regenerative Medicine: From Innovation to Clinical Translation

poster

Successful bone regeneration in clinical research still remains a great challenge due to the complex morphology and the recent advances aim to enhance the rate of bone healing using biofabrication strategies such as 3D bioprinting loaded with growth factors. 3D bioprinting has tremendously boosted the transition from conventional regenerative procedures to customized patient-specific...

150. 3D-printed two-phase GelMA-dextran hydrogel creates 3D structures with large interconnecting porosity for improved cell-support

Rodrigo Salazar Ortiz (RWTH Aachen University Hospital)

15/09/2025, 11:15

T-PS19 Complex architectures and non-planar approaches in Biofabrication

poster

Introduction/Objectives
We have previously shown that an aqueous two-phase system (ATPS) composed of gelatin methacryloyl (GelMA) and dextran can form large interconnected pores via phase separation process [1]. As such open porous gels could be beneficial for 3D tissue engineering, we investigated whether the novel material could be processed by microextrusion and drop-on-demand printing...

181. A 4D Bioprinting Platform to Engineer Anisotropic Musculoskeletal Tissues by Spatially Patterning Microtissues into Temporally Adapting Support Baths

Francesca Diletta Spagnuolo (Trinity College Dublin)

15/09/2025, 11:20

T-PS20 Emerging Bioprinting Platforms for Musculoskeletal Tissue Engineering

poster

Tissue engineering (TE) aims to regenerate damaged or diseased tissues by replicating their native structure, composition, and function. This goal is particularly challenging in the context of musculoskeletal tissues—such as articular cartilage, meniscus, ligaments, and tendons—whose unique biomechanical functions are tightly linked to their extracellular matrix (ECM) architecture. Damage to...

235. A Modular Endoscopic Projection System for Spatially Patterned Photocrosslinking in Cartilage Repair

Theofanis Stampoultzis (ETH)

15/09/2025, 11:25

T-PS11 Biofabrication of soft tissues

poster

A Modular Endoscopic Projection System for Spatially Patterned Photocrosslinking in Cartilage Repair
Theofanis Stampoultzis1, Parth Chansoria1, Marco Raffo2, Amedeo Franco Bonatti2, Giovanni Vozzi2,3, Marcy Zenobi-Wong1*
1Tissue Engineering and Biofabrication Lab, ETH Zurich
2Research Center "E. Piaggio", University of Pisa, Pisa, Italy
3Department of Information Engineering, University of...

472. Advanced 3D Bioprinted Hydrogels as In Vitro Platforms for Breast Cancer Microenvironment Modeling

Giovanni Lo Bello (Magna Græcia University of Catanzaro)

15/09/2025, 11:30

T-PS13 Biofabrication strategies for engineering microarchitectural complexity

poster

Introduction
Breast cancer continues to be one of the leading causes of cancer-related mortality among women worldwide [1,2]. Conventional 2D cultures and animal models fall short in accurately replicating the breast tumor microenvironment, often lacking translational relevance [3]. The development of three-dimensional (3D) in vitro models through hydrogel-based bioprinting offers a promising...

583. A 3D Bioprinted Macroencapsulation System for Efficient Subcutaneous Islet Transplantation

Min Kyeong Kim (UNIST)

15/09/2025, 11:35

T-PS07 Advancing Biofabrication Methods for Macro-Scale Tissue Engineering

poster

Type 1 diabetes mellitus (T1D) is a chronic autoimmune disease that leads to hyperglycemia due to the loss of pancreatic β cells. One of the most effective methods to treat T1D is pancreatic islet transplantation. However, transplanted islets lose their function because of immune reactions. To prevent immune-mediated damage, semipermeable encapsulation strategies are commonly employed....

40. Advancing Pediatric Bone Tissue Engineering: Dipyriamole-Loaded 3D-Printed Bioceramic Scaffolds Promote Stable Bone Formation in a Growing Pig Model During Facial Maturation

Lukasz Witek (NYU College of Dentistry)

15/09/2025, 11:40

T-PS06 Advancing Biofabrication for Regenerative Medicine: From Innovation to Clinical Translation

poster

Pediatric bone tissue engineering presents distinct challenges related to the growing patient including: the need for a construct strategy that preserves growth plates; bone generation that remodels in parallel with skeletal development to prevent long-term growth restrictions; and a degradation profile that aligns with the process of bone generation. Despite the recognized limitations of...

84. Anisotropic microfiber reinforcement facilitate tailored mechanical design in large-scale, biofabricated cartilage constructs

Lennard Spauwen (UMC Utrecht)

15/09/2025, 11:45

T-PS09 Biofabrication of Anisotropy

poster

Introduction
Cartilage defects pose significant challenges in terms of healing. Current treatments have limitations in size, availability, or durability.[1,2] Biofabrication aims to restore tissue functionality by placing biological active components in a pre-defined 3D organization, typically using soft hydrogels for cell preferences.[3] These hydrogels can be mechanically reinforced with...

232. Bioactive Electrospun Nanofiber Membranes for Dental Tissue Engineering and Regeneration

Andrii Lys (Adam Mickiewicz University, NanoBioMedical Centre)

15/09/2025, 11:50

T-PS06 Advancing Biofabrication for Regenerative Medicine: From Innovation to Clinical Translation

poster

Bone defects in the oral and maxillofacial region, often resulting from trauma, congenital anomalies, degenerative conditions, or therapeutic procedures, present significant clinical challenges. Guided bone regeneration (GBR) and guided tissue regeneration (GTR) are widely adopted strategies that rely on barrier membranes to spatially direct tissue growth. However, conventional collagen-based...

30. Biofabrication of Tissue-Specific dECM Hydrogels: Unlocking 3D Bioprinting for Regenerative Medicine

Meenu T S (INDIAN INSTITUTE OF TECHNOLOGY)

15/09/2025, 11:55

T-PS01 Special Session: 20 Years of Bioprinting: Honoring the Past, Shaping the Future

poster

Background: The development of functional tracheal tissue requires both mechanical stability and cellular functionality, yet creating biomimetic tracheal structures remains a significant challenge. In this study, we developed tissue-specific hydrogels derived from decellularized extracellular matrices (ECM) of cartilage, submucosa, and muscle using proprietary methods. In tissue engineering,...

173. BIOINK DEVELOPMENT FOR IN SITU OSTEOCHONDRAL REGENERATION THROUGH MICROEXTRUSION AND FILAMENTED LIGHT BIOPRINTING

Rodrigo Torres García (KU LEUVEN)

15/09/2025, 12:00

T-PS08 Biofabrication for cartilage regeneration and joint preservation

poster

Introduction
Osteoarthritis (OA) is a degenerative disease affecting osteochondral (OC) tissue, leading to pain and joint dysfunction. Current treatments are often limited by availability, efficacy, and cost, highlighting the need for innovative therapeutic approaches. To address this challenge, we propose a novel tool EndoFLight, an advanced in situ 3D bioprinting platform designed for...

133. Biofabrication of the osteochondral unit by replicating its tri-layered architecture: hyaline cartilage, calcified cartilage and subchondral bone

Philipp Fisch (ETH Zürich)

15/09/2025, 12:05

T-PS08 Biofabrication for cartilage regeneration and joint preservation

poster

Introduction: The osteochondral unit composed of subchondral bone, calcified cartilage and hyaline cartilage fulfills a crucial function in joint homeostasis and load transduction. During osteoarthritis, this unit is severely damaged resulting in impaired joint function. Strategies to regain function range from autologous chondrocyte implantation to tissue engineered cartilage to osteochondral...

201. Biohybrid plant extracellular matrix-based humanized bypass grafts for vascular surgery

Marius Dick (Charité – Universitätsmedizin Berlin)

15/09/2025, 12:10

T-PS13 Biofabrication strategies for engineering microarchitectural complexity

poster

Peripheral artery disease is the third leading cause for morbidity worldwide, demanding a multimodal therapy for more than 200 million people. Current therapeutic options for more severe cases range from medication therapy to surgical interventions. Synthetic vascular bypass grafts are the current gold standard in the surgical treatment of patients with no suitable autologous graft available....

168. Biphasic Electrospun Structure to Treat Periodontitis

Lidia Vaculenco (Polytechnic University of Leiria-Centre for Rapid and Sustainable Product Development)

15/09/2025, 12:15

T-PS13 Biofabrication strategies for engineering microarchitectural complexity

poster

Periodontal disease(PD) is a chronic infection caused by gram-negative bacteria, with a high prevalence worldwide. It is considered the second leading cause of dental problems.The disease begins with an imbalance between the oral microbiota and the host’s immune system, triggering vascular changes and inflammation.Common symptoms include bleeding and swollen gums, which compromise tissue...

52. Bioprinted tissues towards standardized industrial applications: Combination of physiological collagen bioink and fabrication techniques in standardizable design

Tobias Weigel (Fraunhofer ISC)

15/09/2025, 12:20

T-PS11 Biofabrication of soft tissues

poster

Introduction
The standardizability in fabrication of any biological tissues in high numbers is a major promise of the field of biofabrication. The acceptance of biofabrication methods in the industry continues to be hampered by the fact that bioinks are assembled in non-physiological structures (especially for soft tissues) combined with an absent application-orientated model design.
With...

47. Breast cancer cells isolated from the brain form functional cell-cell interactions with brain cells and adapt to the brain extracellular matrix

Esra Türker (Institute of Clinical Neurobiology)

15/09/2025, 12:25

T-PS11 Biofabrication of soft tissues

poster

Three-dimensional (3D) cellular models to study various kind of diseases mimic a more in <span style="box-sizing:border-box; margin:0px; padding:0px">vivo-like</span> native environment compared to 2D cellular models. Our study focuses on breast cancer, which represents the second most common cancer to metastasize to the brain. Triple-negative breast cancer, HER2+, and Luminal B breast...

35. Development of a high-throughput combinatorial microfluidic assisted 3D bioprinter for artificial skeletal muscle tissue screening

Maede Pajouhande (Institute of physical chemistry-Polish academy of sciences)

15/09/2025, 12:30

T-PS20 Emerging Bioprinting Platforms for Musculoskeletal Tissue Engineering

poster

Despite significant advancements in 3D bioprinting, challenges remain in achieving high printing speed, efficiency, and homogeneity in biological samples. These limitations constrain the practical application of bioprinting in tissue engineering, particularly in the fabrication of complex tissues like skeletal muscle. This project introduces a novel high-throughput combina torial...

39. Enhancing keratocyte lineage differentiation of bone marrow-derived mesenchymal stromal cells via 3D culture for in vivo corneal bioprinting applications.

Alexandre Taoum (Center for Molecular Cell Biology (ZMBH), Heidelberg University)

15/09/2025, 12:35

T-PS06 Advancing Biofabrication for Regenerative Medicine: From Innovation to Clinical Translation

poster

Introduction: Corneal transplantation is the gold standard procedure to cure corneal diseases that can lead to blindness. Fabrication of corneal tissues is a promising solution to overcome the shortage of human donors. Our future goal is to utilize a bioprinter mounted to a robotic arm to print corneal tissue directly onto the eye of the patient. One interesting cell type for in situ and in...

96. Engineering of Perfused 3D Hepatocellular Carcinoma Tissue Model

Michal Uflewski (Polbionica lnc.)

15/09/2025, 12:40

T-PS07 Advancing Biofabrication Methods for Macro-Scale Tissue Engineering

poster

Introduction
For decades, two-dimensional (2D) cell culture systems have been fundamental for studying cellular metabolism, differentiation, and drug efficacy. These simple models enable straightforward experimental design but does not replicate native tissue complexity. Important features such as physiological cell density, structural organization, and vascularization are absent. Recently,...

99. Expanding the Melt-Electro Fibrillation Polymer Library for Advanced Biofabrication Applications

Tamaki Kumauchi (University of Würzburg , Department of Functional Materials in Medicine and Dentistry)

15/09/2025, 12:45

T-PS09 Biofabrication of Anisotropy

poster

Expanding the Melt-Electro Fibrillation Polymer Library for Advanced Biofabrication Applications
Tamaki Kumauchi1, Kristina Andelovic1 and Jürgen Groll1
1Department of Functional Materials in Medicine and Dentistry, Institute of Functional Materials and Biofabrication (IFB), and Bavarian Polymer Institute (BPI), University of Würzburg, 97070 Würzburg, Germany

Introduction: Melt-Electro...

146. Detergent-free pancreatic decellularization

Paweł Mirosław (Polbionica lnc)

15/09/2025, 12:50

T-PS11 Biofabrication of soft tissues

poster

Introduction
Tissue decellularization is widely used in tissue engineering and regenerative medicine. Currently, most established decellularization methods use detergents, which have long decellularization processes with inconsistent results. Residual chemicals used in decellularization or changes in the biochemistry and structure of extracellular matrix (ECM) proteins may be responsible for...

124. Development of the mushroom-chitosan-based bioink for bone tissue regeneration

Joonyoung Kim (Sungkyunkwan University School of Medicine)

15/09/2025, 12:55

T-PS07 Advancing Biofabrication Methods for Macro-Scale Tissue Engineering

poster

Chitosan, a naturally derived polysaccharide, has gained significant attention in tissue engineering due to its excellent biocompatibility, biodegradability, and bioactivity. However, conventional chitosan sourced from crustacean shells poses limitations such as allergenicity and ethical concerns. In this study, we extracted and characterized mushroom-derived chitosan from Pleurotus ostreatus...

138. Development of a Vascularization-Enhancing 3D Printable Fibrin-Gelatin Interpenetrating Network Bioink for Sustained Release Local Drug Delivery

Tazrin Islam Dipti (Chonnam National University, College of Agriculture and Life Sciences (CALS))

15/09/2025, 13:00

T-PS06 Advancing Biofabrication for Regenerative Medicine: From Innovation to Clinical Translation

poster

Conventional local drug delivery systems often fail to support sustained drug release, while many biomaterials used in tissue engineering and transplantation lack the necessary stability, biocompatibility, and capacity to support vascularization required for long-term graft survival and function. In order to overcome these restrictions, 3D bioprinting has become a potent technique that makes...

196. Engineering Human Glomerular Filtration Barrier In Vitro for Disease Modeling and Drug Testing

Eleonora Fiorentini (Istituto di Ricerche Farmacologiche Mario Negri IRCCS)

15/09/2025, 13:05

T-PS02 3D complex architectures from stem cells

poster

Introduction: The glomerular filtration barrier (GFB) is a highly specialized structure responsible for blood filtration in the kidney; is composed of podocytes, glomerular basement membrane and fenestrated endothelial cells. Dysfunction of this barrier is a hallmark of many glomerular diseases. However, the current systems in vitro cannot mimic efficiently the 3D organization and the...

151. Fabricating microfibrillar fiber bundles as cell-guiding additive for bioprinting

Sven Heilig (University of Wuerzburg)

15/09/2025, 13:10

T-PS09 Biofabrication of Anisotropy

poster

Introduction
Two main technologies of Biofabrication are bioprinting and scaffold generation. [1] Bioprinting can be used with cells in the matrix, while scaffold generation is cell-free and cells are attached afterwards. Both have their distinct advantages, e.g. bioprinting enables the generation of complex tissue hierarchies in one step, while scaffolds can guide cell elongation via...

208. Development of Polycaprolactone Fibrous Scaffolds for 3D In Vitro Osteochondral Modelling: Influence of Scaffold Morphology on Cell Distribution and Proliferation

Edvardas Bagdonas (State Research Institute, Centre for Innovative Medicine)

15/09/2025, 13:15

T-PS08 Biofabrication for cartilage regeneration and joint preservation

poster

Introduction
Cartilage tissue regeneration has been significantly advanced through the development of artificial scaffolds, including three-dimensional (3D) electrospun structures. A key challenge in designing in vitro osteochondral models is creating scaffolds with a functional barrier that mimics the native tidemark—separating cartilage and bone—while still permitting cellular communication...

230. Development of patient specific composite scaffold using 3D printing for regeneration of craniofacial bone tissue

Monireh Kouhi (Isfahan University of Medical Sciences)

15/09/2025, 13:20

T-PS06 Advancing Biofabrication for Regenerative Medicine: From Innovation to Clinical Translation

poster

Development of patient specific composite scaffold using 3D printing for regeneration of craniofacial bone tissue
Monireh Kouhi1*, Mohammad Khodaei2, Saba Yousefi3
1. Dental Materials Research Center, Dental Research Institute, School of Dentistry, Isfahan University of Medical Sciences, Isfahan 81746-73461, Iran,
2. Materials Engineering Group, Golpayegan College of Engineering, Isfahan...

548. Creation and optimization of 3D bioprinted perfusable in vitro model to study cancer metastasis to bone

Łukasz Luśtyk (Warsaw University of Technology)

15/09/2025, 13:25

poster

Introduction:
Cancer is one of the leading causes of death worldwide and although developing new therapies can help fight this disease, cancers which origins from breast, lung or prostate can undergo metastasis process leading to development of secondary tumors in other parts of the human body [1]. Bone is the organ to which cancer often metastases and to pioneer cancer therapies, creation of...

563. Design and characterization of novel composite hydrogels as bioink base for bone tissue engineering via the endochondral ossification pathway

Łukasz Matusiak (Warsaw University of Technology)

15/09/2025, 13:30

poster

Among the challenges associated with the regeneration of critical-sized bone defects, the most significant issue is the insufficient delivery of oxygen and nutrients, which impedes the optimal development of osteocytes. A potential solution lies in the use of biomaterials that can induce bone formation from hypertrophic chondrocytes cartilage tissue via endochondral ossification. For the...

55. HIGH-THROUGHPUT CUSTOM SYSTEMS FOR BIOMATERIALS SCREENING AND BIOLOGICAL ANALYSIS OF CENTIMETRE-SCALE MUSCLES

Maryia Piletskaya (ICHF PAN)

15/09/2025, 13:35

T-PS21 From Bulk to Micro-Architecture: Hydrogel Engineering and Bio-Fabrication for Skeletal Tissue Applications

poster

Skeletal muscle tissue engineering is emerging as a cornerstone in the development of in vitro models, offering unprecedented opportunities to study muscle physiology and pathology. This work aim to develop high-throughput, custom-designed system for fabricating skeletal muscle constructs at a centimetre scale, addressing challenges in scalability, reproducibility, and biological...

68. Impact of cellular interactions on microarchitecture, matrix remodeling, and tenogenesis in bioreactor stimulated 3D tendon model

Amrutha Datla (Indian Institute of Technology Hyderabad)

15/09/2025, 13:40

T-PS21 From Bulk to Micro-Architecture: Hydrogel Engineering and Bio-Fabrication for Skeletal Tissue Applications

poster

Impact of cellular interactions on microarchitecture, matrix remodeling, and tenogenesis
in bioreactor stimulated 3D tendon model
Amrutha Datla, Subha Narayan Rath*
Regenerative Medicine and Stem cell Laboratory, Indian Institute of Technology Hyderabad, India - 502284
ABSTRACT:
Introduction: Tendon injuries are widespread, often leading to tendinopathy due to lack of
early recognition,...

117. From Ink to Organ Function: Advanced Strategies for the Vascularization of Bioprinted Bionic Organs

Palina Milewska (Polbionica lnc.)

15/09/2025, 13:45

T-PS06 Advancing Biofabrication for Regenerative Medicine: From Innovation to Clinical Translation

poster

Introduction
One of the most significant challenges in organ bioengineering is developing functional vascular networks. Proper vascularization is critical for transporting oxygen, nutrients, and signaling molecules, while also removing waste. In bionic organs, poor vessel formation limits nutrient exchange and cell migration, reducing transplant quality and long-term survival [1], [2]. The...

128. Fabrication of GelMA/ColMA Hydrogel Microfluidic Model to study vascular endothelial cells

Marzie Torkashvand (Masaryk University)

15/09/2025, 13:50

T-PS11 Biofabrication of soft tissues

poster

Introduction:
On-chip vascular microfluidic models provide powerful platforms for studying vasculature and its diseases in vitro. These models enable focused investigation of specific vascular layers, such as the endothelium, and the influence of hemodynamics on it. While traditional plastics or glass-based fabrication allows for defined microchannel architecture, its inherent stiffness and...

171. Fabrication of chitosan/Gallic acid/ Strontium Chloride/ polycaprolactone nanofibers for bone regeneration

Shokoufeh Mehrtashfar (University of Tehran)

15/09/2025, 13:55

T-PS08 Biofabrication for cartilage regeneration and joint preservation

poster

Considering the increasing incidence of bone-degenerative diseases and injuries, including osteoarthritis, especially in societies where aging is associated with increased obesity and poor physical activity, the repair of bone defects is one of the major challenges in medical science. Due to the difficulties, high cost, risks of surgery, severe allergic reactions, and ultimately rejection of...

205. Fabrication of a Biomimetic Scaffold from Decellularized Goat Urinary Bladder for Urinary Bladder Reconstruction

Akshay Kawale (D Y Patil Education Society, Deemed to be University)

15/09/2025, 14:00

T-PS06 Advancing Biofabrication for Regenerative Medicine: From Innovation to Clinical Translation

poster

Decellularized scaffolds are becoming important tools within tissue engineering. This work compares the effectiveness of three decellularization protocols—SDS, H₂O₂, and Triton X-100 for goat urinary bladder tissue on the preservation of ECM components and the functionality of scaffolds. The cellular removal and ECM preservation were assessed through histological staining with H&E,...

216. Histological processing of polycaprolactone scaffolds

Tomas Ragauskas (State Research Institute Center for Innovative Medicine)

15/09/2025, 14:05

T-PS08 Biofabrication for cartilage regeneration and joint preservation

poster

Introduction
Cell-seeded scaffolds made from natural or synthetic materials are widely tested in animal models as biodegradable implants for treatment of joint disease (1). One of the most commonly used material for scaffold production is polycaprolactone (PCL), known for its biocompatibility and mechanical properties close to human cartilage. To validate cell distribution within scaffold and...

43. Nanofiber-Based Delivery of Crocus Sativus Phenolics Protects Against Chemotherapy-Induced Hepatotoxicity

Nima Sabouri (Department of Biology, Mashhad Branch, Islamic Azad University)

15/09/2025, 14:10

T-PS06 Advancing Biofabrication for Regenerative Medicine: From Innovation to Clinical Translation

poster

<div style="direction: ltr;">Introduction: </div> <div style="direction: ltr;">Hepatotoxicity induced by cisplatin (CP), a widely-used chemotherapeutic agent, significantly hampers its therapeutic efficacy. Oxidative stress due to reactive oxygen and nitrogen species plays a critical role in CP-induced liver injury. Crocus sativus (saffron), known for its phenolic compounds and...

54. Introducing Optical Fiber-Assisted Bioprinting (OFAB) as Novel 3D Bioprinting Method

Maximilian Pfeiffle (Julius Maximilians Universität Würzburg)

15/09/2025, 14:15

T-PS07 Advancing Biofabrication Methods for Macro-Scale Tissue Engineering

poster

Introducing Optical Fiber-Assisted Bioprinting (OFAB) as Novel 3D Bioprinting Method
Maximilian Pfeiffle, Alessandro Cianciosi, Tomasz Jüngst
Department for Functional Materials in Medicine and Dentistry, University of Würzburg, Pleicherwall 2, 97070 Würzburg, Germany
Introduction: To accelerate scientific progress in tissue engineering and regenerative medicine, new accessible 3D...

57. Integrated MEW-MES Scaffold and Hydrogel for Nasal Septum Regeneration

Yakui Liu (Technische Universität Dresden)

15/09/2025, 14:20

T-PS07 Advancing Biofabrication Methods for Macro-Scale Tissue Engineering

poster

Introduction: Nasal septum defects, whether resulting from infection, trauma, or prior surgery, remain difficult to repair due to shortcomings in existing implant materials [1]. Conventional implants often suffer from inadequate mechanical strength, rapid degradation, or insufficient bioactive cues for both cartilage and mucosal regeneration [1]. As a result, patients risk poor functional...

59. Phycocyanin-Integrated GelMA Hydrogels for Cartilage Tissue Engineering

Ayse Kose (KU Leuven)

15/09/2025, 14:25

T-PS08 Biofabrication for cartilage regeneration and joint preservation

poster

Osteoarthritis (OA) is one of the most prevalent musculoskeletal disorders globally, with its burden escalating due to the aging population and the absence of disease-modifying therapies 1. Despite its debilitating nature, current treatments remain palliative, focusing primarily on pain management or surgical intervention, with no curative options. The pathogenesis of OA involves a complex...

82. Microfluidics-Enabled Synthesis of Lipid Nanoparticles for miRNA Cellular Transfection

Alicja Kosik-Kozioł (Institute of Fundamental Technological Research, Polish Academy of Sciences)

15/09/2025, 14:30

T-PS06 Advancing Biofabrication for Regenerative Medicine: From Innovation to Clinical Translation

poster

Introduction
Lipid nanoparticles (LNPs) represent a promising and versatile platform for the non-viral delivery of genetic material, including microRNA (miRNA), which plays a crucial regulatory role in gene expression. While LNPs have already demonstrated clinical success as mRNA carriers in vaccines, most notably in COVID-19 immunization strategies, their application in miRNA delivery opens...

85. Laser-Induced forward transfer (LIFT) for 2.5D deterministic patterning of pre-vascular structures with high spatial complexity in open-top synovial Organ-on-Chip (OoC)

Núria Ginés Rodriguez (Department of Orthopaedics, University Medical Center Utrecht)

15/09/2025, 14:35

T-PS13 Biofabrication strategies for engineering microarchitectural complexity

poster

INTRODUCTIO 
The synovial lining is responsible to produce synovial fluid into the joint capsule. The synovial fluid acts as a lubricating and protecting layer for the articular cartilage to ensure pain-free frictionless movement of the articular joint. The synovial lining is prone to inflammation from injury, overuse or inflammatory arthritis (1), but modelling these events in vitro, while...

90. Melt Electrofibrillation Enables Control over Type II Collagen Alignment in Engineered Cartilage Constructs

Lennard Spauwen (UMC Utrecht)

15/09/2025, 14:40

T-PS08 Biofabrication for cartilage regeneration and joint preservation

poster

Introduction
Cartilage defects present significant challenges in long-term repair, with current treatments, such as cell-based therapies, often failing to restore sustained biomechanical function due to poor integration and/or lack of type II collagen organization[1]. The native depth-dependent fiber orientations in the arched collagen structure provide the mechanical support necessary to...

91. Melt electrowriting PCL scaffolds to reinforce 3D bioprinted full thickness cornea

Ekaterina Takmakova (University of Helsinki, Department of Chemistry)

15/09/2025, 14:45

T-PS13 Biofabrication strategies for engineering microarchitectural complexity

poster

Corneal blindness is one of the leading causes of blindness worldwide. A cornea transplant surgery provides ultimate cure, however, it is restricted by donor tissue shortage. Thus, we aim to develop 3D bioprinted full thickness corneas to address this lack of donor material. To ensure robust transport, handling, and suturing, the bioprinted cornea's mechanical properties needs to be improved....

100. Multispheroid Bioassembly through Meltelectrowriting of a Precisely Arranged Fibrous Architecture for Tissue Models

Camilla Mussoni (University of Würzburg)

15/09/2025, 14:50

T-PS13 Biofabrication strategies for engineering microarchitectural complexity

poster

Introduction
Over the past few decades, extensive research has been actively conducted for the fabrication of human tissues to, amongst many applications, understand the effects of a wide range of chemicals on human health and the environment (1). Thus, the need for the development of innovative assessment tools that provide reliable results in identifying and regulating the risks of...

106. Optimization of dual crosslinked alginate and gelatin bioink for the biofabrication of 3D tumor models

Alicia Bonilla Vázquez (Instituto de Química de São Carlos - Universidade de São Paulo (IQSC - USP))

15/09/2025, 14:55

T-PS06 Advancing Biofabrication for Regenerative Medicine: From Innovation to Clinical Translation

poster

Introduction:
The low success rate of oncological drugs in clinical trials highlights the need for predictive preclinical models because the traditional 2D cultures and animal models fail to replicate human tumor microenvironments fully. The researchers have seen 3D bioprinting as a promising technology for the fabrication of more physiologically relevant tissue models. Bioinks for such...

116. Injectable Nanofibrous Microcarriers with Tunable PVA/Tannic Acid Ratios for Controlled miRNA Delivery in Intervertebral Disc Regeneration

Farzaneh Sabbagh (Institute of Fundamental Technological Research, Polish Academy of Sciences (IPPT PAN))

15/09/2025, 15:00

T-PS06 Advancing Biofabrication for Regenerative Medicine: From Innovation to Clinical Translation

poster

Injectable Nanofibrous Microcarriers with Tunable PVA/Tannic Acid Ratios for Controlled miRNA Delivery in Intervertebral Disc Regeneration

Farzaneh Sabbagh, Paweł Nakielski
Institute of Fundamental Technological Research, Polish Academy of Sciences (IPPT PAN), Warsaw, Poland

Introduction: Degenerative disc disease (IDD) induces persistent back discomfort resulting from the degeneration...

160. Improved standardization, scalability and convergence of fiber based biofabrication approaches for anisotropic tissues

Zan Lamberger (University of Würzburg , Department of Functional Materials in Medicine and Dentistry)

15/09/2025, 15:05

T-PS09 Biofabrication of Anisotropy

poster

Introduction: Reproducibility, scalability and adaptability are crucial aspects for any fabrication method that desires to address cell laden materials that shall be used for tissue engineering or drug screening approaches. Biomimetic fiber-based scaffolds are the most prominent among these as they mimic the fibrillar nature of many ECM proteins or other fibrous structures found therein, such...

188. Production of cell-laden hydrogel microparticle via ruthenium-catalyzed photocrosslinking within coaxial microfluidic system

Mehdi Khanmohammadi

15/09/2025, 15:10

T-PS11 Biofabrication of soft tissues

poster

Introduction
Injectable hydrogels with submicron dimensions that can provide both mechanical support and biological functionality to encapsulated cells are gaining attention for in vivo delivery of therapeutic cells and biomolecules [1,2]. In recent developments, hydrogel crosslinking triggered by visible light using the ruthenium(II) tris-bipyridyl complex (Ru) in conjunction with sodium...

41. Quercetin-derived carbon dots promote proliferation and migration of Schwann cells and enhance neurite outgrowth

Phanindra Babu Kasi (Uppsala University)

15/09/2025, 15:15

T-PS06 Advancing Biofabrication for Regenerative Medicine: From Innovation to Clinical Translation

poster

Quercetin, a flavonoid known for its antioxidant properties, has recently garnered attention as a potential neuroprotective agent for treatment of the injured nervous system. The repair of peripheral nerve injuries hinges on the proliferation and migration of Schwann cells, which play a crucial role in supporting axonal growth and myelination. In this study we synthesized Quercetin-derived...

49. Revolutionizing Tissue Regeneration: An ECM-Integrated Hydrogel System for Next-Generation Biofabrication

Junaid Kashir (Khalifa University)

15/09/2025, 15:20

T-PS11 Biofabrication of soft tissues

poster

Introduction: Advancements in biofabrication are poised to revolutionize healthcare by providing innovative solutions to complex medical challenges. A recent area of excitement is the integration of the extracellular matrix (ECM), which plays a pivotal role in tissue homeostasis, cellular signalling, and regenerative processes, into biofabrication approaches, making it the ECM a critical...

88. Regulatory and Safety Challenges for Natural Biomaterials in Bioprinting and Tissue Engineering for Clinical Applications

Michał Wesołowski (Polbionica Inc.)

15/09/2025, 15:25

T-PS11 Biofabrication of soft tissues

poster

Introduction
Natural biomaterials have opened promising avenues in bioprinting and tissue engineering by providing native-like environments for regenerative therapies. These materials offer significant biological advantages but also introduce challenges related to variability, immunogenicity, and contamination risks [1]. The regulatory framework is gradually evolving to address these...

184. Region specific bioprinting of microtissues for meniscus tissue engineering via dual localized growth factor delivery

Francesca Diletta Spagnuolo (Trinity College Dublin)

15/09/2025, 15:30

T-PS13 Biofabrication strategies for engineering microarchitectural complexity

poster

The meniscus plays a critical role in load transmission, shock absorption, and joint stability within the knee. However, its limited regenerative capacity, particularly in the inner avascular zone, contributes to the progression of degenerative joint diseases following injury. The complex zonal organization of the meniscus—characterized by a fibrous outer zone rich in type I collagen and a...

206. The Embryonic Envelope Reimagined: Biofabrication of a Decellularized Chorionic Scaffold for Urinary Bladder Tissue Engineering

Akshay Kawale (D Y Patil Education Society, Deemed to be University)

15/09/2025, 15:35

T-PS06 Advancing Biofabrication for Regenerative Medicine: From Innovation to Clinical Translation

poster

Decellularized human chorionic membrane (HCM) offers a promising biomaterial for tissue engineering due to its rich extracellular matrix (ECM), inherent biocompatibility, and accessibility. This study compares the efficacy of different decellularization methods in generating acellular HCM scaffolds while preserving structural and functional ECM integrity. Cellular removal and ECM preservation...

198. Tailoring Biomaterial Ink Properties with Nanomaterials: POSS and Polydopamine for Next-Generation Bone Tissue Scaffolds

Andreea Ioana Dinu (National University of Science and Technology Politehnica Bucharest)

15/09/2025, 15:40

T-PS07 Advancing Biofabrication Methods for Macro-Scale Tissue Engineering

poster

Introduction Significant efforts have concentrated on creating various synthetic and natural biomaterials that mimic the native bone extracellular matrix, promote osteogenic differentiation, and improve effective bone regeneration. 3D printing has become a widely used fabrication method for scaffolds, facilitating the accurate mapping of the 3D structure of bone defects [1]. In this research,...

223. Rheological characterization of alginate bioinks for application in corneal implant bioprinting

Mikołaj Gąbka (AGH University of Krakow)

15/09/2025, 15:45

T-PS06 Advancing Biofabrication for Regenerative Medicine: From Innovation to Clinical Translation

poster

Corneal disorders, including trauma, infections, and degenerative diseases, are among the major causes of blindness. Due to the global shortage of donor corneas and risks associated with transplantation, there is a growing interest in developing bioprinted corneal implants as an alternative therapeutic approach.
The aim of this study was to evaluate an alginate-based bioink. In the first...

562. Simplified 3D model for invasion testing: complexified interactions between osteosarcoma cells and bone-mimicking PLGA/20TCP scaffolds

Ewa Walejewska (Warsaw University of Technology)

15/09/2025, 15:50

poster

Introduction
Osteosarcoma (OS) is a rare and aggressive primary bone tumor affecting children and adolescents. Traditional 2D models fail to replicate the complexity of bone–tumor interactions.
Aim: to develop a hybrid 3D osteosarcoma model replicating interactions between healthy and malignant bone tissues.
Methods
Healthy bone-mimicking scaffolds were fabricated using TCP-enriched (20...

180. Reproducible in vitro vascularization via high throughput molding of sacrificial scaffolds

Patrick Kuntschke (University Hospital Wuerzburg)

15/09/2025, 15:55

T-PS07 Advancing Biofabrication Methods for Macro-Scale Tissue Engineering

poster

Introduction:
Replicating physiologically relevant tissue environments in vitro requires both sophisticated biological design and reliable scalable fabrication. Current approaches often rely on complex biofabrication methods such as stereolithography (SLA) and melt electrowriting (MEW), which are time-intensive, laborious, and lack reproducibility at scale [1,2]. To overcome these...

135. Towards volumetric scaffold fabrication for regenerative medicine using robotic additive manufacturing

Vivek Cherian David (Maastricht University , MERLN Institute for Technology Inspired Regenerative Medicine)

15/09/2025, 16:00

T-PS19 Complex architectures and non-planar approaches in Biofabrication

poster

Introduction
Robotic additive manufacturing (RAM) is currently being explored to overcome the limitations of layer-by-layer additive manufacturing technologies in the fabrication of complex constructs for regenerative medicine (RM). A few successful attempts at using RAM for in-situ extrusion-based bioprinting have been reported, where the fabrication is non-planar but still...