Electrospinning and Metal Stents – A Good Fit?

Jun 30, 2022, 4:20 PM
10m
Room: S3 A

Room: S3 A

Speaker

Kanari, Konstantina (The Electrospinning Company Ltd )

Description

"Micro- and nanofibrous materials have attracted the interest of the scientific community for the better part of ~30 years, due to their unique properties and potential for applications. Electrospinning is a technique that can produce micro- and nanofibers fast, repeatedly, and with tailored morphology. When fibres are electrospun from biocompatible polymers then they can be used in numerous medical applications such as tissue engineering, regenerative medicine, implant coatings, medical textiles, etc. This academic focus has slowly translated into a number of medical devices containing electrospun biomaterials becoming clinically available. The particular area of interest for this presentation is the use, substitution, and improvement that electrospun textiles offer in the field of medical textiles as metal stent coatings.

A brief overview of the state-of-the-art of woven textiles as well as in use in metal stents will be given, as well as a summary of existing electrospun metal stent coverings available now or in clinical trials.

At The Electrospinning Company Ltd we design, develop and manufacture advanced micro- and nanofibrous materials. These biocompatible materials can be used in a range of different biomedical applications, including wound care, cell therapy, and cardiovascular devices. Currently our materials are being used in at least four FDA-approved medical devices that are in the clinical trial stage.

Together with our partners we are developing different types of electrospun textiles for various metal stent applications. We will present data on direct comparisons between traditional textiles and electrospun textiles and their performance in different metal stent applications, such as EVAR, TEVAR, occluders, and covered vascular stents. Examples of the parameters discussed are diffusion across the coverings, blocking of particles, as well as adhesion to the metal frame.

As a centre of excellence in electrospinning biocompatible materials, we have an in-depth understanding on the relationship between material characteristics, like fibre morphology and architecture, and their suitability for specific applications. Therefore, it is paramount to ensure that these characteristics remain stable while the adhesion of the fibres on the different substrates is enhanced."

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