Conveners
S03+S33 3D printing of bionic organs – how far are we from clinical application? + From Bench-to-Bedside: Translating 3D Printing Applications in Tissue Engineering and Regenerative Medicine
- Anahita Ahmadi Soufivand (University of Erlangen-Nuremberg (Friedrich-Alexander-Universität Erlangen-Nürnberg))
- Marta Klak (Foundation of Research and Science Development)
- Jakub Rybka (Center for Advanced Technology, Adam Mickiewicz University in Poznan )
- James E. Smay
- Lukasz Witek (Department of Biomaterials, NYU College of Dentistry/Assistant Professor )
"Introduction
Type 1 diabetes (T1D) is a disease, which affects milions of patients. Islet or pancreatic transplantation is a method of treating complicated T1D. The limitation of these methods is the lack of organs for transplantation. 3D-bioprinting using living cells could be a solution. We present results of bioprinted bionic pancreas on mouse and pig model.
Materials and...
"Tracheal damage is associated with the narrowing, weakening and discontinuity of the conductive part of the lower respiratory tract. Extensive defects cannot undergo end-to-end anastomosis and current approaches present poor outcomes due to weak mechanical properties, poor re-epithelialisation and vascularisation of the implanted graft. Herein, we investigated the use of collagen-based...
Extensive defects of the upper extremity cause significant patient burden, including disability and social stigma. Approximately, 500,000 bone defects are reconstructed annually in the USA alone at a cost of ~$2.5 billion, due to factors including donor site harvest and lengthy operative times. Bone defects >5cm are usually reconstructed with autologous vascularized bone transfer (bone from...
"Introduction. Irrespective of the several scaffold designs that have been investigated in the last 30 years, the actual number of scaffold guided bone tissue engineering (SGBTE) approaches that were able to reach clinical application are few. Most of these approaches fail translation into clinical settings firstly because outcomes of scaffold design properties and host immune responses...
INTRODUCTION
With a growing demand for effective regenerative medicine therapies, more sophisticated tissue-engineered in vitro models are required for a better understanding of the fundamental biological processes that underlie regeneration. To tackle this need and further comprehend these processes, new technologies are emerging in the tissue-engineering field. The state-of-the-art...
"INTRODUCTION
One of the main functions of guided bone regeneration (GBR) barriers are to preserve the bone graft and maintain its mechanical stability during the healing process. Personalized metallic meshes meet GBR demands as well as a good predictable tissue regeneration1. Although they offer good performance in terms of tissue regeneration, these metallic meshes present several...
Introduction: Contemporary reconstructive approaches for critical-sized bone defects carry significant disadvantages. As a result, clinically driven research has focused on the development and translation of alternative therapeutic concepts. Scaffold guided tissue regeneration (SGTR) is an emerging technique to heal critical-sized bone defects. However, issues synchronising scaffold...
The knee meniscus plays an indispensable role in articular surface protection, shock absorption, and stress transmission. Meniscus injuries are extremely prevalent, with an annual incidence of 66 to 70 per 100,000 people. Due to limited vascularization, the regenerative capacity of the meniscus is relatively low and restricted to the most vascularized outer regions. The most commonly performed...
