Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Conference 2022

Session

PS08 Antimicrobial biomaterials for bone regeneration

PS08

Not scheduled

ICE Krakow

825. Drop on demand printing of a polymer-based composite releasing the antimicrobial peptide SAAP-148 on titanium to prevent orthopaedic infections

Riool, Martijn (Amsterdam UMC)

poster

INTRODUCTION: Fracture fixation devices (FFD) have infection rates ranging from 5 to 10% for closed fractures and even higher rates up to 30% for open fractures1 causing a devastating complication. Clinically, implant infections are prevented by systemic antibiotic prophylaxis, the placement of antibiotic laden bone cements, and the use of minimally invasive surgical procedures2. However,...

827. FUNCTIONAL ε-POLYLYSINE/HYALURONIC ACID HYDROGELS WITH ANTIBACTERIAL ACTIVITY

Sceglovs, Artemijs (1 Rudolfs Cimdins Riga Biomaterials Innovations and Development Centre of RTU 2 Baltic Biomaterials Centre of Excellence, Headquarters at Riga Technical University )

poster

Introduction
Large infection spreading rates combined with increasing microbial resistance to antibiotics remain one of the biggest healthcare challenges. In this context, biomaterials based on natural biopolymers with antibacterial properties have recently come to the fore as potential candidate vehicles as both preventative measures and treatments of severe infections. In this study,...

830. Polyphenols and mesoporous bioactive glasses doped with therapeutic ions as biofunctional additives for PCL-based composites

Chęcińska, Kamila (Department of Glass Technology and Amorphous Coatings, AGH University of Science and Technology )

poster

Introduction: The growing requirements for tissue engineering results in the design of new materials, including polymer composites with various modifying phases. In addition, active substances can modify the properties of materials, and thus the human body's response. For this purpose, polymer-ceramic composites with various mesoporous glass (MBGs) modifying phases were designed. Numerous...

824. Silver-doped calcium titanate layer with in vivo bone-bonding ability to fight bone bacterial infection in titanium implants

Piñera Avellaneda, David (Universitat Politècnica de Catalunya )

poster

Introduction
The rapid integration in the bone tissue and the prevention of bacterial infection are key for the success of the implant. In this regard, a silver (Ag) doped thermochemical treatment that generates an Ag-doped calcium titanate layer on titanium (Ti) surface was previously developed by our group in order to improve the bone-bonding ability and provide antibacterial activity 1....