Small-diameter synthetic vascular grafts do not recapitulate native blood vessel’s structural heterogeneity, which in the case of arteries, is based on the morphologically distinct tunica intima, media, and adventitia. These layers differ in composition and as a result in their specific function [1].
It can be then speculated that when one of these structures is neglected in the design of a...
Introduction
Poly(alkylene citrate)s – (PACs) are widely studied as candidates to produce temporary medical devices such as blood vessel prostheses, wound dressings, drug delivery systems, scaffolds, and matrices for tissue engineering. The advantages of PACs are susceptibility to hydrolytic degradation and the possibility of modification with free radical scavengers, which are known to tune...
From 2020's WHO data, Ischemic heart disease is already the world's leading cause of death, and it also brings a high burden to the world. Nowadays, almost all clinical therapies based on supportive therapies, not is curative therapies, which cannot regenerate myocardial tissue. If using heart transplantation, there has not been resolved yet that donated hearts will be little supply and the...
