Wounding affects us all, yet the mechanisms of healing are still a partial mystery. In particular the events immediately unfolding when a tissue is wounded are difficult to capture, and are thus understudied und incompletely understood. Studying wounding responses in ex vivo skin is an elegant strategy to explore immediate wounding responses. Using ex vivo skin from both human and pig has...
Introduction
Bone grafting is among the most frequent forms of transplantation, utilized to manage a variety of bone defect cases. Enriching synthetic bone substitutes with immune-interacting properties can be a strategy to improve their performance. The host’s response to e.g. microbial components can result in both a positive or negative effect on bone formation. As an immunomodulatory...