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Abstract. This paper presents a study of the applicability of the MeDiNa pavement design methodology, a mechanistic-empirical software developed in Brazil, to the Portuguese pavement structures. The paper describes the main features and assumptions of the MeDiNa software, and compares the predicted pavement performance indicators, such as cracking and rutting, with the Portuguese specifications and pavement design practice. The paper also discusses the data requirements and challenges for using the MeDiNa software in a different country, and suggests some future developments, such as local calibration, integration with pavement management systems, and prediction of the International Roughness Index. The paper concludes that the MeDiNa software could be a useful tool for road agencies in Portugal, but it would need comprehensive and wide data collection and adaptation to the Portuguese context.