"Introduction. With limited treatment options for acute brain injuries like stroke or traumatic brain injury, recent research has focused on the development of immune-modulating and pro-regenerative therapies for brain diseases. TSG-6 (tumor necrosis factor-alpha stimulated protein 6) is a multifunctional protein with attractive therapeutic potential for neurological applications. As for...
Introduction: 2D pnictogens, including bismuthene, have recently emerged as new members of the ever-increasing 2D family thanks to their exceptional electronic, topological, thermoelectronic, and optical properties.
Here we present a 2D bismuthene synthesized from the 3D bulk bismuth involving a surfactant-assisted chemical reduction method to improve its magnetic properties...
Glioblastoma (GBM) is the most common (60-70% of primary brain tumours) and the most malignant of the glial tumours. Although current therapies remain palliative, they have been proved to prolong overall survival. The effectiveness of temozolomide (TMZ) chemotherapy is limited by the serious systemic and dose-related side effects. Therefore, the primary goal of the presented studies was the...
"Introduction:
The ongoing search for novel drug delivery to a target site has led to increased interest in using bioorthogonal organometallic (BOOM) chemistry for localised prodrug activation. Anticancer prodrugs containing a palladium (Pd)-cleavable propargyl protecting group have been developed, necessitating a suitable method to deliver the palladium nanoparticle (PdNP) catalyst to a...
"Smart-materials based dynamically activated microenvironments for tissue engineering
C. Ribeiroa,b, S. Ribeiroa, M. M. Fernandesa,b, N. Castroc, V. Correiaa,d, U. Silvanc,e, and
S. Lanceros-Mendezc,e
aCentro de Física, Universidade do Minho, 4710-057, Braga, Portugal
bCenter of Biological Engineering, University of Minho, Braga 4710-057 Portugal
cBCMaterials, Basque Center for...
