The conquest of Alexander the Great had a significant impact on the coin production of Carian mints, similarly as in most of the territories subdued by the Macedonian king. His successors and their officials minted in their own names, while civic mints continuing to strike their own coins. The next century was marked in Caria by a continuous struggle for power of Ptolemaic, Seleucid, and Antigonid rulers which was followed by the emergence of an ever-powerful island city: Rhodes, which would influence a number of Carian mints, especially after the treaty of Apameia in 188 BC. By then, Rome had become the key player and the kingmaker in western Asia Minor. Rome's influence and imprint are not always visible on the coinages of a century and a half which preceded Augustus whose rule represents a defining turning point for the local coinages of Caria for the next three centuries.