Speaker
Description
Transcranial magnetic stimulation (TMS) is an innovative therapeutic technique for the treatment of psychiatric and neurological disorders. Its interaction with the brain tissue is still not fully understood. Numerical dosimetry can provide insights, however there is no consensus on the preferred observable to be evaluated.
This study proposes a novel observable for TMS numerical dosimetry: the effective electric field (Eeff). This quantity is the E-field component parallel to the local orientation of cortical and white matter axons. Through an experimental proof of concept, it is shown how Eeff better correlates with TMS induced muscle response, compared to traditionally observed quantities. This study is the first to extract Eeff in both white and grey matter and by demonstrating the correlation between Eeff and muscle response to TMS, it introduces a novel observable for future TMS dosimetric studies, potentially enhancing its precision.
