Speaker
Description
Three-dimensional (3D) in vitro cell cultures are the foundation of tissue engineering, enabling the reconstruction of tissues outside the body for research and therapeutic applications. While underutilized in bioelectromagnetism (BioEM) research, 3D cultures offer a more biologically relevant alternative to traditional 2D models and a more ethical, scalable, and cost-effective option than animal testing. The 3D in vitro models provide new opportunities for studying how cells and tissues respond to electric, magnetic, and electromagnetic fields and interact with novel materials sensitive to such fields. This talk will outline practical aspects for generating 3D cultures and detecting the experimental effects, principles of selecting the 3D in vitro models for BioEM purposes, and real-world applications of these platforms. Finally, it will also explore cross-disciplinary integration, highlighting how BioEM can not only benefit from using the 3D cultures but also contribute to advancing extracorporeal tissue reconstruction and preservation, nanotechnology and pharmacological research. These synergies have the potential to improve experimental reproducibility while reducing reliance on animal models, support the transition towards more sustainable research practices, and accelerate the clinical translation of scientific discoveries.
