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This study explores how transcranial alternating current stimulation (tACS) influences neural oscillations, which are critical for brain function and can be disrupted in neurological disorders. tACS, a non-invasive neuromodulation technique, applies low-intensity electrical currents to modulate cortical activity. However, the precise effects of stimulation frequency and intensity on neural entrainment remain unclear.
Using a microscale neural model of the cortical column, the study simulates alpha and gamma rhythms to examine how tACS affects different neuron types within a realistic network. The findings indicate that tACS entrains neuron activity through phase locking, but the degree of entrainment varies based on stimulation frequency and neuron type. These insights help refine neuromodulation strategies for treating conditions like epilepsy by improving our understanding of how tACS interacts with neural circuits.
