22–27 Jun 2025
Couvent des Jacobins
Europe/Paris timezone

PA-27 A novel RF exposure system for live cell imaging in real time under confocal microscopy: a preliminary design

23 Jun 2025, 16:30
1h 30m
Halle 1 (Couvent des Jacobins)

Halle 1

Couvent des Jacobins

Speaker

Fulvio Schettino

Description

The aim of this work is to present the preliminary design of a novel exposure system in FR2 band, to fit with the confocal inverted microscope stage for real-time analysis of biological samples. The setup is a cylindrical metallic cavity, suitable for hosting Fluorodish FD35-WPI, with ITO-coated glasses on the top and on the bottom, to allow the analysis at confocal microscope. Conventional ITO coating demonstrated to have poor performance, so a customized index-matched ITO-coated glass was manufactured and used. The overall idea of the design is presented, with some preliminary results of system characterization and numerical dosimetry. In particular, it is shown that a Coefficient of Variation lower than 30% can be achieved in a wide region of the exposed sample. The optimization of the system is currently underway, in its final steps, and the final setup will be presented at the conference. After completing the numerical dosimetry, and the proper experimental validation, field distribution maps will be released in order to facilitate the analysis from the biological perspective

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