Speaker
Description
The time-varying low- to intermediate-frequency (primarily between 1 Hz and 100 kHz) electromagnetic fields excite nerves and muscles through induced electric fields. This phenomenon, called the “stimulus effect”, is the biological basis for international guidelines for the protection of the human body. However, scientific uncertainty has been identified regarding the thresholds for peripheral nerve stimulation, particularly in the intermediate-frequency range above 10 kHz. Further clarification is needed on the thresholds associated with the sensation of pain which is associated with health risks. To address this, we are currently developing a multi-electrode array device to accurately assess the threshold of stimulus effects related to pain sensation using axon bundles extended from human induced pluripotent stem cell-derived sensory neural spheroids. In this presentation, we will outline the development of this device and present preliminary results from the evaluation of stimulus-induced responses.
