22–27 Jun 2025
Couvent des Jacobins
Europe/Paris timezone

Study of the effects of 5G modulated-700 mhz radiofrequency fields on the cellular stress response in astrocytes and sh-sy5y neuroblastoma cells.

25 Jun 2025, 09:30
15m
Les Dortoirs (Couvent des Jacobins)

Les Dortoirs

Couvent des Jacobins

Speaker

Emilie Puginier

Description

The potential biological impact of 5G signals at 700 MHz on cellular processes such as oxidative stress, cell proliferation, and apoptosis remains an open question. In this study, we investigated the effects of such environmental radiofrequency field (RF) exposure on both primary astrocytes derived from rat brains and human SH-SY5Y neuroblastoma cells, focusing on these key cellular pathways and stress-related markers. Specific Absorption Rates (SAR) of 0.08 and 4 W/kg were tested over two exposure durations: 1 hour and 24 hours. After each exposure, analyses were performed either immediately or 24 hours post-exposure to evaluate potential delayed effects.
ROS levels, proliferation rates, and apoptotic markers were measured under all conditions. Analyses for primary astrocytes are complete, showing no significant changes in mitochondrial oxidative stress, cell proliferation, or apoptosis under any of the conditions tested.
Our findings support the conclusion that, under controlled in vitro conditions, exposure to 5G-modulated 700 MHz does not have detectable effects on primary rat astrocytes.
The experiments for SH-SY5Y cells are still ongoing and the results will be presented at the congress.

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