Speaker
Akimasa Hirata
Description
This study examines Aδ- and C-fiber activation thresholds using intraepidermal electrical stimulation (IES) and computational modeling. Anodal stimulation activated Aδ-fibers with single pulses, while C-fibers required multiple pulses. Cathodal stimulation failed to activate C-fibers, indicating a higher perception threshold. Computational modeling validated experimental results, refining stimulation protocols for selective small-fiber activation. The findings contribute to neuropathic pain diagnostics and international neural stimulation guidelines.