BioEM 2025

Session

Workshop 2

WS2

23 Jun 2025, 13:30

Les Dortoirs (Couvent des Jacobins)

Conveners

Workshop 2: Computational and clinical neuroscience, Epilepsy, Transcranial Stimulation

• Mariam Al Harrach

22. tACS in Cortical Neuronal Network: a Microscale Computational Study

Mariam Al Harrach

23/06/2025, 13:30

This study explores how transcranial alternating current stimulation (tACS) influences neural oscillations, which are critical for brain function and can be disrupted in neurological disorders. tACS, a non-invasive neuromodulation technique, applies low-intensity electrical currents to modulate cortical activity. However, the precise effects of stimulation frequency and intensity on neural...

23. Computational modeling of frequency-dependent neocortical response to thalamic neurostimulation in epilepsy

Linda Iris Joseph Tomy

23/06/2025, 13:52

The application of centromedian stimulation (CMS) has been limited by the lack of clarity regarding its mode of action. In this study, we used stereoelectroencephalography (SEEG) signals from a patient with focal cortical dysplasia. The suppression of neocortical interictal activity with CMS was frequency-dependent: no effect at 50 Hz, 15s suppression at 100Hz and ~2s suppression at 70 and 150...

24. Modeling the Effects of tDCS on Whole-Brain dynamics of Epileptogenic Networks

Mehmet Alihan Kayabas

23/06/2025, 14:14

Delivering low-intensity electrical currents through scalp electrodes, using transcranial Direct Current Stimulation (tDCS) can modulate the membrane potential of cortical neurons and may potentially restore the balance of excitability in epileptogenic networks. Optimizing the efficacy of tDCS to decrease the frequency of seizures requires a better understanding of tDCS impact on brain...

25. Patient-Specific Deep Learning for IED Detection in tDCS Epilepsy Treatment: A Synthetic DataAugmented Approach

Mathias Peuvrier

23/06/2025, 14:36

Transcranial direct current stimulation (tDCS) shows promise for drug-resistant epilepsy patients, but monitoring treatment efficacy remains challenging. While current monitoring relies on subjective seizure diaries, electroencephalogram (EEG) recordings offer a more objective approach through the detection of interictal epileptiform discharges (IEDs). However, automated IED detection faces...